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EFEMP2 gene

Known as: EGF-CONTAINING FIBULIN-LIKE EXTRACELLULAR MATRIX PROTEIN 2, FIBULIN 4, EFEMP2 
National Institutes of Health

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EFEMP1 genefibulin-4

Papers overview

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2019
2019
EFEMP2 promotes colon cancer cell invasion and growth through the ERK1/2 signaling pathway.
EFEMP2 is an extracellular matrix (ECM) glycoprotein that is a pivotal oncogene in tumor progression and metastasis. However, the… 
2017
2017
FBLN4 as candidate gene associated with long-term and short-term survival with primary glioblastoma
Background Glioblastoma multiforme (GBM) is the most common malignant and lethal type of primary central nervous system tumor in… 
2015
2015
EFEMP2 is upregulated in gliomas and promotes glioma cell proliferation and invasion.
Gliomas are the most common and aggressive form of primary brain tumor. Although EGF-containing fibulin-like extracellular matrix… 
2015
2015
Fibulin-4 E57K Knock-in Mice Recapitulate Cutaneous, Vascular and Skeletal Defects of Recessive Cutis Laxa 1B with both Elastic Fiber and Collagen Fibril Abnormalities*
Background: Mutations in fibulin-4 cause autosomal recessive cutis laxa 1B, characterized by loose skin with vascular, lung, and… 
2015
2015
Abnormal mechanosensing and cofilin activation promote the progression of ascending aortic aneurysms in mice
Aortic aneurysms may form when smooth muscle cells cannot respond appropriately to external mechanical forces. Aberrant… 
2014
2014
Elastin development-associated extracellular matrix constituents of subepithelial connective tissue in human pterygium.
PURPOSE We evaluated the expression of several extracellular matrix constituents implicated in the synthesis and reticulation of… 
2013
2013
Longer Term Survival of a Child With Autosomal Recessive Cutis Laxa Due to a Mutation in FBLN4
Autosomal recessive cutis laxa (ARCL) is a clinically and genetically heterogeneous group of disorders characterized by loose… 
2011
2011
Chronic Lung Disease in Cutis Laxa
BACKGROUND: Cutis laxa (CL) is a group of disorders characterized by loose, inelastic, and redundant skin. The different types of… 
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