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E2F5 gene

Known as: E2F transcription factor 5, E2F5 
 
National Institutes of Health

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E2F5 Transcription Factor

Papers overview

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2016
2016
E2f4 and E2f5 are essential for the development of the male reproductive system.
The E2F transcription factors are primarily implicated in the regulation of entry and exit from the cell cycle. However, in vivo… Expand
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2016
2016
miR-132 targeting E2F5 suppresses cell proliferation, invasion, migration in ovarian cancer cells.
Accumulating evidence showed that microRNA-132 (miR-132) are involved in development and progression of several types of cancers… Expand
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2016
2016
The transcription factor FOXN3 inhibits cell proliferation by downregulating E2F5 expression in hepatocellular carcinoma cells
Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related death worldwide, and the mechanisms underlying the… Expand
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2016
2016
miRNA-154-5p Inhibits Proliferation, Migration and Invasion by Targeting E2F5 in Prostate Cancer Cell Lines.
BACKGROUND MicroRNAs (miRNAs) are a class of small non-coding RNAs (18-25 nucleotides) which post-transcriptionally regulate gene… Expand
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2016
2016
Deregulated E2F5/p38/SMAD3 Circuitry Reinforces the Pro-Tumorigenic Switch of TGFβ Signaling in Prostate Cancer.
Transforming growth factor-β signaling exerts divergent effects on normal and cancer cells, although mechanism underlying this… Expand
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2015
2015
MicroRNA-34a targets FMNL2 and E2F5 and suppresses the progression of colorectal cancer.
Colorectal cancer (CRC) is one of the most common malignancies. Increasing evidences indicate that dysregulation of miRNAs is a… Expand
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2011
2011
A potential oncogenic role of the commonly observed E2F5 overexpression in hepatocellular carcinoma.
AIM To explore the expression pattern of E2F5 in primary hepatocellular carcinomas (HCCs) and elucidate the roles of E2F5 in… Expand
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2007
2007
E2F5 and LEK1 translocation to the nucleus is an early event demarcating myoblast quiescence.
Raf/MEK/ERK signaling in skeletal muscle cells affects several aspects of myogenesis that are correlated with the duration and… Expand
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Highly Cited
2000
Highly Cited
2000
E2F4 and E2F5 play an essential role in pocket protein-mediated G1 control.
E2F transcription factors are major regulators of cell proliferation. The diversity of the E2F family suggests that individual… Expand
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2000
2000
Human E2F5 gene is oncogenic in primary rodent cells and is amplified in human breast tumors.
E2F transcription factors (E2F1 to 6) are central players in the control of animal cell proliferation as regulators of genes… Expand
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