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E 5090

Known as: E-5090, E5090 
National Institutes of Health

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2 relations

Broader (2)

AcrylatesNaphthols

Papers overview

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1996
1996
IL-1 is an important mediator for microcirculatory changes in endotoxin-induced intestinal mucosal damage
Although small intestine is frequently injured in endotoxin shock, the exact pathological sequence has not been fully understood… 
1991
1991
Drugs in Inflammation
Reducing the Side-Effects of Anti-Inflammatory Drugs.- Towards safer nonsteroidal anti-inflammatory drugs.- Developing… 
1991
1991
A novel inhibitor of IL-1 generation, E5090: in vitro inhibitory effects on the generation of IL-1 by human monocytes.
E5090 is an orally active inhibitor of IL-1 generation, being converted in vivo into the pharmacologically active deacetylated… 
1991
1991
A novel inhibitor of IL-1 generation, E5090: in vivo inhibitory effect on the generation of IL-1-like factor and on granuloma formation in an air-pouch model.
The in vivo production of IL-1-like activity was investigated in the exudate of a rat air-pouch inflammatory model. An… 
1991
1991
Antiinflammatory properties of E5090, a novel orally active inhibitor of IL-1 generation.
E5090 is a novel orally active inhibitor of IL-1 generation without cyclooxygenase-inhibiting activity. The effects of E5090 on… 
1991
1991
Pharmacological properties of E5090, an orally active inhibitor of IL-1 generation.
E5090 is a newly synthesized orally active inhibitor of IL-1 generation without cyclooxygenase inhibiting activity form. Orally… 
1991
1991
A NOVEL INHIBITOR OF IL-1 GENERATION, E5090 : SYNTHESIS AND STRUCTURE ACTIVITY RELATIONSHIPS OF 3-(4-HYDROXY-1-NAPHTHALENYL)-2-PROPENOIC ACIDS
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