Ductal Breast Carcinoma In Situ and Lobular Carcinoma In Situ

Invasive lobular carcinoma (ILC) is the second most prevalent histologic subtype of invasive breast cancer. Here, we… (More)

Human models of noninvasive breast tumors are limited, and the existing in vivo models do not mimic inter- and intratumoral… (More)

Immunohistochemical analysis of E-cadherin has changed the way lobular neoplasia is perceived. It has helped to classify… (More)

Claudins are transmembrane proteins that seal tight junctions, and are critical for maintaining cell-to-cell adhesion in… (More)

Pancreatic ductal adenocarcinoma ranks among the most lethal of human malignancies. Here, we assess the cooperative interactions… (More)

Loss of heterozygosity (LOH) allows the expression of recessive mutation in tumor suppressor genes (TSG). Therefore, on the basis… (More)

AIMS The mutual relation of lobular carcinoma in situ (LCIS) and ductal carcinoma in situ (DCIS) of the breast, as accepted… (More)

Invasive breast cancer shows a wide range of morphological differentiation, associated with differences in prognosis, but as yet… (More)

The epithelial-specific cell-cell adhesion molecule E-cadherin was analyzed immunohistochemically on tissue sections of 89 human… (More)

One hundred ninety-six whole human breasts were examined by a subgross sampling technique with histologic confirmation. The… (More)