Drug Repositioning

Known as: Drug Repurposing, Repositioning, Drug, Repurposing, Drug 
The deliberate and methodical practice of finding new applications for existing drugs.
National Institutes of Health

Topic mentions per year

Topic mentions per year

2006-2018
010020020062018

Papers overview

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2015
2015
A system-level identification of drug-target direct interactions is vital to drug repositioning and discovery. However, the… (More)
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Highly Cited
2013
Highly Cited
2013
UNLABELLED Small cell lung cancer (SCLC) is an aggressive neuroendocrine subtype of lung cancer with high mortality. We used a… (More)
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2013
2013
Recent advances in computational biology suggest that any perturbation to the transcriptional programme of the cell can be… (More)
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2013
2013
: Existing computational methods for drug repositioning either rely only on the gene expression response of cell lines after… (More)
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2013
2013
Drug repositioning, exemplified by sildenafil and thalidomide, is a promising way to explore alternative indications for existing… (More)
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2013
2013
Recent in vivo studies showed new hopes of drug repositioning through causality inference from drugs to disease. Inspired by… (More)
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Highly Cited
2012
Highly Cited
2012
Drug-target interaction (DTI) is the basis of drug discovery and design. It is time consuming and costly to determine DTI… (More)
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Highly Cited
2012
Highly Cited
2012
1. Weaver, T., Maurer, J. & Hayashizaki, Y. Nat. Rev. Genet. 5, 861–866 (2004). 2. Fan, M., Tsai, J., Chen, B., Fan, K. & LaBaer… (More)
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2012
2012
Side-effects are the unintended consequence of therapeutic treatments, but they can also be seen as valuable read-outs of drug… (More)
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Highly Cited
2010
Highly Cited
2010
A bottleneck in drug discovery is the identification of the molecular targets of a compound (mode of action, MoA) and of its off… (More)
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