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Drug Agonism

Known as: Agonism, Drug 
Phenomena and pharmaceutics of compounds that selectively bind to a specific receptor and trigger a response. They mimic the action of endogenous… Expand
National Institutes of Health

Papers overview

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2015
2015
Type 4 metabotropic glutamate (mGlu4) receptors are emerging targets for the treatment of various disorders. Accordingly… Expand
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2014
2014
Activation of β3-adrenoceptors has been shown to have a direct relaxant effect on urinary bladder smooth muscle from both rats… Expand
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Highly Cited
2013
Highly Cited
2013
Glucagon, an essential regulator of glucose homeostasis, also modulates lipid metabolism and promotes weight loss, as reflected… Expand
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Highly Cited
2013
Highly Cited
2013
Background—To assess cardiovascular actions of APJ agonism during prolonged (Pyr1)apelin-13 infusion and renin–angiotensin system… Expand
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Review
2007
Review
2007
  • T. Kenakin
  • Molecular Pharmacology
  • 2007
  • Corpus ID: 5963117
This article describes functional selectivity of agonists and antagonists and distinguishes conventional cell-based functional… Expand
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Highly Cited
2007
Highly Cited
2007
A range of ligands displayed agonism at the long isoform of the human dopamine D2 receptor, whether using receptor-G protein… Expand
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2006
2006
This study evaluated the ability of A1 and A3 adenosine receptor (AR) agonism, and A1, A2A, A2B and A3AR antagonism (revealing… Expand
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2005
2005
Dexmedetomidine, a highly selective &agr;2-adrenoceptor agonist, is used in combination with local anesthetics for sedation and… Expand
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Highly Cited
2003
Highly Cited
2003
G protein-coupled receptors (GPCRs) are allosteric proteins that adopt inactive (R) and active (R*) conformations in equilibrium… Expand
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2000
2000
Evidence exists for a state of sympathetic hyperactivity in essential hypertension, and moxonidine, a new central sympathetic… Expand
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