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Doxazosin Mesylate

Known as: 1 (4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-((2,3-dihydro-1,4-benzodioxin-2-yl)carbonyl)piperazine, Doxazosin Mesylate [Chemical/Ingredient], Mesylate, Doxazosin 
The mesylate salt form of doxazosin, a quinazoline compound with smooth muscle relaxing activity. Doxazosin mesylate selectively antagonizes alpha-1… 
National Institutes of Health

Related topics

Related topics

14 relations
Adrenergic alpha-Antagonists [MoA]Adrenergic alpha1-Antagonists [MoA]Arterial Vasodilation [PE]Decreased Blood Pressure [PE]

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Doxazosin

Papers overview

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2003
2003
Altered pharmacokinetics and excessive hypotensive effect of candesartan in a patient with the CYP2C9*1/*3 genotype
Highly Cited
2002
Highly Cited
2002
Stability-indicating methods for the determination of doxazosin mezylate and celecoxib.
Highly Cited
2002
Highly Cited
2002
Successful blood pressure control in the African American Study of Kidney Disease and Hypertension.
BACKGROUND The African American Study of Kidney Disease and Hypertension (AASK) is an ongoing trial to evaluate the effect of… 
2000
2000
Double–Blind Trial of the Efficacy and Tolerability of Doxazosin in the Gastrointestinal Therapeutic System, Doxazosin Standard, and Placebo in Patients with Benign Prostatic Hyperplasia
Background: The α1–blocker doxazosin mesylate is an established efficacious and welltolerated treatment for benign prostatic… 
Highly Cited
1999
Highly Cited
1999
Clinical pharmacokinetics of doxazosin in a controlled-release gastrointestinal therapeutic system (GITS) formulation.
AIMS A controlled-release gastrointestinal therapeutic system (GITS) formulation of doxazosin mesylate, a long-acting selective… 
Highly Cited
1997
Highly Cited
1997
Relationships of quality-of-life measures to long-term lifestyle and drug treatment in the Treatment of Mild Hypertension Study.
OBJECTIVES To compare 5 antihypertensive drugs and placebo for changes in quality of life (QL). To assess the relationship of… 
Highly Cited
1995
Highly Cited
1995
Comparison of five antihypertensive monotherapies and placebo for change in left ventricular mass in patients receiving nutritional-hygienic therapy in the Treatment of Mild Hypertension Study (TOMHS…
BACKGROUND Increased left ventricular mass (LVM) by echocardiography is associated with increased risk of cardiovascular disease… 
Highly Cited
1993
Highly Cited
1993
Treatment of Mild Hypertension Study: Final Results
Objective. —To compare six antihypertensive interventions for the treatment of mild hypertension. Design. —Randomized, double… 
Highly Cited
1993
Highly Cited
1993
Treatment of Mild Hypertension Study. Final results. Treatment of Mild Hypertension Study Research Group.
OBJECTIVE To compare six antihypertensive interventions for the treatment of mild hypertension. DESIGN Randomized, double-blind… 
Highly Cited
1993
Highly Cited
1993
The treatment of mild hypertension study.
To the Editor. —The Treatment of Mild Hypertension Study (TOMHS) 1 represents a worthy contribution to the evaluation of… 
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