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Dose-dependent

Refers to the effects of treatment with a drug. If the effects change when the dose of the drug is changed, the effects are said to be dose-dependent… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
NTHi induction of Cxcl2 and middle ear mucosal metaplasia in mice
Chronic otitis media (COM) develops after sustained inflammation and is characterized by secretory middle ear epithelial… 
2010
2010
Getting a Notch Closer to Understanding Diabetic Kidney Disease
Diabetic kidney disease (DKD) is one of the most devastating complications of diabetes. Renal dysfunction develops in about one… 
Highly Cited
2009
Highly Cited
2009
Ribavirin dose reduction raises relapse rate dose‐dependently in genotype 1 patients with hepatitis C responding to pegylated interferon alpha‐2b plus ribavirin
Summary.  The impact of ribavirin exposure on virologic relapse remains controversial in combination therapy with pegylated… 
2004
2004
The Effect of Inflammatory Cytokines on Secretion of Macrophage Colony‐Stimulating Factor and Monocyte Chemoattractant Protein‐1 in Human Granulosa Cells
Problem:  In order to investigate the role of macrophage colony‐stimulating factor (M‐CSF) and monocyte chemoattractant protein… 
1997
1997
Preventive effect of ritodrine hydrochloride and/or urinary trypsin inhibitor against lipopolysaccharide‐induced preterm delivery in mice
Background. The purpose of this study was to confirm the preventive effect of ritodrine hydrochloride (ritodrine) alone or… 
Highly Cited
1993
Highly Cited
1993
Dose-dependent differences in the profile of mutations induced by (+)-7R,8S-dihydroxy-9S,10R-epoxy-7,8,9,10-tetrahydrobenzo(a)pyrene in the coding region of the hypoxanthine (guanine…
Chinese hamster V-79 cells were exposed to a high dose (0.30-0.48 microM; 32% cell survival), an intermediate dose (0.04-0.10… 
1993
1993
Bone inductive potential and dose-dependent response of bovine bone morphogenetic protein combined with type IV collagen carrier.
Using type IV collagen as carrier, the expression of bovine bone morphogenetic protein (bBMP) activity and the relation of… 
1988
1988
Role of hypovolemic hemoconcentration in dose-dependent flow decline observed in murine tumors after intraperitoneal administration of glucose or mannitol.
Responses of tumor microcirculation (RBC flux) to i.p. glucose or mannitol injections were studied in early generation… 
Highly Cited
1978
Highly Cited
1978
Restoration of the Acute Insulin Response by Sodium Salicylate: A Glucose Dose-related Phenomenon
Adult-onset diabetics have markedly diminished or absent acute insulin responses to glucose that can be partially restored by… 
Highly Cited
1965
Highly Cited
1965
HUMORAL AND CELLULAR ASPECTS OF THE IMMUNE RESPONSE TO THE SOMATIC ANTIGEN OF SALMONELLA ENTERITIDIS
A study was made of the cellular and humoral aspects of the immune response of the rabbit to the somatic polysaccharide of… 
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