Dose-dependent

Refers to the effects of treatment with a drug. If the effects change when the dose of the drug is changed, the effects are said to be dose-dependent… (More)
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
Established tumors are typified by an immunosuppresive microenvironment. Countering this naturally occurring phenomenon, emerging… (More)
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Highly Cited
2013
Highly Cited
2013
BACKGROUND The stability and propagation of hepatitis C virus (HCV) is dependent on a functional interaction between the HCV… (More)
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Highly Cited
2006
Highly Cited
2006
RNA interference (RNAi) is a universal and evolutionarily conserved phenomenon of post-transcriptional gene silencing by means of… (More)
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Highly Cited
2005
Highly Cited
2005
Observational studies suggest a longer duration of breastfeeding to be associated dose dependently with a decrease in risk of… (More)
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Highly Cited
2004
Highly Cited
2004
UNLABELLED The safety and bone antiresorptive effect of a single subcutaneous dose of AMG 162, a human monoclonal antibody to… (More)
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Highly Cited
2004
Highly Cited
2004
OBJECTIVE This study evaluated the ability of the incretin mimetic exenatide (exendin-4) to improve glycemic control in patients… (More)
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Highly Cited
2003
Highly Cited
2003
The Oct-3/4 transcription factor sustains embryonic stem (ES) cell self-renewal and is a dose-dependent cell fate determinant. In… (More)
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Highly Cited
2002
Highly Cited
2002
Tumor growth is angiogenesis dependent. We hypothesized that nonneoplastic tissue growth also depends on neovascularization. We… (More)
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Highly Cited
2001
Highly Cited
2001
Minocycline, a semisynthetic tetracycline derivative, protects brain against global and focal ischemia in rodents. We examined… (More)
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Highly Cited
1997
Highly Cited
1997
Recent data have identified leptin as an afferent signal in a negative-feedback loop regulating the mass of the adipose tissue… (More)
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