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Direct Thrombin Inhibitor [EPC]

Known as: Direct Thrombin Inhibitor 
National Institutes of Health

Papers overview

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Review
2016
Review
2016
Novel oral anticoagulants for heparin-induced thrombocytopenia
Abstract To review the use of the novel oral anticoagulant (NOAC) agents for the treatment of heparin-induced thrombocytopenia… 
2012
2012
Strategies for the Management of Suspected Heparin-Induced Thrombocytopenia
AbstractBackground: Heparin-induced thrombocytopenia (HIT) is a rare but serious complication of heparin therapy. The diagnosis… 
2012
2012
Assessing the impact of a heparin-induced thrombocytopenia protocol on patient management, outcomes and cost
Summary Establishing the diagnosis of heparin induced thrombocytopenia (HIT) is challenging as laboratory tests for HIT vary in… 
Review
2011
Review
2011
A clinical-laboratory algorithm incorporating optical density value to predict heparin-induced thrombocytopenia
Summary The diagnosis of heparin-induced thrombocytopenia (HIT) is complex and involves integrating both clinical and laboratory… 
2011
2011
Effect of a Direct Thrombin Inhibitor Compared with Dalteparin and Unfractionated Heparin on Human Osteoblasts
Purpose: Osteoporosis is a relevant problem after long term administration of unfractionated heparin (UFH) and low molecular… 
Review
2011
Review
2011
Oral Thromboprophylaxis Following Total Hip or Knee Replacement: Review and Multicentre Experience with Dabigatran Etexilate
The risk of venous thromboembolism (VTE) in patients undergoing total knee or hip replacement surgery is high. As a result… 
Review
2010
Review
2010
Rationale and design of the PREVENT-HIT study: a randomized, open-label pilot study to compare desirudin and argatroban in patients with suspected heparin-induced thrombocytopenia with or without…
Review
2008
Review
2008
Standardizing the management of heparin-induced thrombocytopenia.
PURPOSE An evidence-based heparin- induced thrombocytopenia (HIT) treatment protocol to standardize the management of confirmed… 
Review
2005
Review
2005
Effect of Lepirudin on the International Normalized Ratio
BACKGROUND: Many patients receiving direct thrombin inhibitor (DTI) therapy require transition to warfarin. This transition may… 
2004
2004
The inhibitory effect of melagatran, the active form of the oral direct thrombin inhibitor ximelagatran, compared with enoxaparin and r-hirudin on ex vivo thrombin generation in human plasma.
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