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Direct Thrombin Inhibitor [EPC]

Known as: Direct Thrombin Inhibitor 
 
National Institutes of Health

Papers overview

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Review
2014
Review
2014
Dabigatran is an oral direct thrombin inhibitor (DTI) licensed for stroke prevention in atrial fibrillation and likely to be soon… Expand
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2012
2012
New anticoagulants, like the orally available direct thrombin inhibitor (DTI) dabigatran etexilate, have recently been introduced… Expand
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Highly Cited
2010
Highly Cited
2010
BACKGROUND The diagnosis of heparin-induced thrombocytopenia (HIT) is challenging. Over-diagnosis and over-treatment are common… Expand
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Review
2010
Review
2010
Anticoagulation with oral vitamin K antagonists (VKA) is the mainstay of the treatment of venous and/or arterial thromboembolism… Expand
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2010
2010
BACKGROUND Thrombin generation (TG) in plasma can be monitored continuously with a fluorogenic thrombin substrate using… Expand
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Highly Cited
2008
Highly Cited
2008
Heparin-induced thrombocytopenia (HIT) is a life-threatening immune response to heparin that is associated with a high risk of… Expand
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Highly Cited
2007
Highly Cited
2007
AIMS The novel direct thrombin inhibitor (DTI), dabigatran etexilate (Boehringer Ingelheim Pharma GmbH & Co. KG), shows potential… Expand
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Highly Cited
2007
Highly Cited
2007
Dabigatran is a reversible and selective, direct thrombin inhibitor (DTI) undergoing advanced clinical development as its orally… Expand
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2003
2003
OBJECTIVES The effects of ximelagatran, an oral direct thrombin inhibitor (DTI), recombinant hirudin (r-hirudin) and enoxaparin… Expand
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Review
2003
Review
2003
The inability of the heparin-antithrombin complex to inhibit fibrin-bound thrombin limits the utility of heparin for treatment of… Expand
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