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Dimethylglycine Dehydrogenase

Known as: Dehydrogenase, Dimethylglycine, Dimethylglycine Dehydrogenase [Chemical/Ingredient], N,N-dimethylglycine oxidoreductase 
A FLAVOPROTEIN enzyme that catalyzes the oxidative demethylation of dimethylglycine to SARCOSINE and FORMALDEHYDE.
National Institutes of Health

Related topics

Related topics

8 relations
DMGDH geneIn BloodProcess of secretionantagonists & inhibitors
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Papers overview

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2018
2018
Oxysterol species: reliable markers of oxidative stress in diabetes mellitus
PurposeTo assess the plasma oxysterol species 7-ketocholesterol (7-Kchol) and cholestane-3β,5α,6β-triol (chol-triol) as… Expand
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2013
2013
Glycine Betaine as a Direct Substrate for Methanogens (Methanococcoides spp.)
ABSTRACT Nine marine methanogenic Methanococcoides strains, including the type strains of Methanococcoides methylutens, M… Expand
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2013
2013
Scavenging of free-radical metabolites of aniline xenobiotics and drugs by amino acid derivatives: toxicological implications of radical-transfer reactions.
We investigated a novel scavenging mechanism of arylamine free radicals by poly- and monoaminocarboxylates. Free radicals of… Expand
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Highly Cited
2008
Highly Cited
2008
Copper/amino acid catalyzed cross-couplings of aryl and vinyl halides with nucleophiles.
Copper-assisted Ullmann-type coupling reactions are valuable transformations for organic synthesis. Researchers have extensively… Expand
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Highly Cited
2007
Highly Cited
2007
Characterization of oxysterols by electrospray ionization tandem mass spectrometry after one-step derivatization with dimethylglycine.
We report a novel approach to derivatize the primary, secondary, and tertiary hydroxy group(s) of oxysterols with N,N… Expand
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Highly Cited
2006
Highly Cited
2006
N,N-dimethyl-beta-alanine as an inexpensive and efficient ligand for palladium-catalyzed Heck reaction.
N,N-Dimethyl-beta-alanine was found to be a more powerful phosphine-free ligand than the previously reported ligand, N,N… Expand
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2006
2006
Synthesis and structure of cyclic oligo(p-phenylene oxide)s, -(C6H4O)n- (n = 6-10).
Stepwise growth of oligo(p-phenylene oxide)s and cyclization via the Ullmann coupling reaction by using CuI/N,N-dimethylglycine… Expand
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2001
2001
Cloning of dimethylglycine dehydrogenase and a new human inborn error of metabolism, dimethylglycine dehydrogenase deficiency.
Dimethylglycine dehydrogenase (DMGDH) (E.C. number 1.5.99.2) is a mitochondrial matrix enzyme involved in the metabolism of… Expand
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Highly Cited
1993
Highly Cited
1993
Serum betaine, N,N-dimethylglycine and N-methylglycine levels in patients with cobalamin and folate deficiency and related inborn errors of metabolism.
Homocysteine and 5-CH3-tetrahydrofolate (5-CH3-THF) are converted to methionine and THF by the CH3-cobalamin (CH3-Cbl)-dependent… Expand
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1989
1989
Characterization of a [3H]glycine recognition site as a modulatory site of the N-methyl-D-aspartate receptor complex.
A [3H]glycine recognition site in rat brain synaptic plasma membranes (SPM) has been identified, having characteristics expected… Expand
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