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Dimaprit
Known as:
Carbamimidothioic acid, 3-(dimethylamino)propyl ester
, Dimaprit [Chemical/Ingredient]
A histamine H2 receptor agonist that is often used to study the activity of histamine and its receptors.
National Institutes of Health
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Related topics
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12 relations
Narrower (4)
APT compounds
Dimaprit Dihydrochloride
SK&F 91488
nordimaprit
Broader (1)
Histamine Agonists
In Blood
agonists
analogs & derivatives
antagonists & inhibitors
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
1986
1986
Cimetidine inhibition of dimaprit-induced writhing in the rat.
C. Scarpignato
,
P. del Soldato
Pharmacology
1986
Corpus ID: 46824291
Intraperitoneal, but not intravenous administration of dimaprit (50-125 mg/kg) caused a dose-dependent writhing in the rat. This…
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1986
1986
The effect of the new H2-receptor antagonist mifentidine on gastric secretion, gastric emptying and experimental gastric and duodenal ulcers in the rat: comparison with cimetidine and ranitidine.
C. Scarpignato
,
M. Tangwa
,
R. Tramacere
,
P. del Soldato
Digestion
1986
Corpus ID: 3324090
The new H2-receptor antagonist mifentidine (DA 4577) was tested for its antisecretory and gastric motor effects in comparison…
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1985
1985
Histamine release during an experimental coronary thrombosis in awake dog
E. Masini
,
J. Phanchenault
,
F. Pezziardi
,
P. Gautier
,
J. Gagnol
Agents and Actions
1985
Corpus ID: 22641086
Histamine is released into the systemic circulation during anaphylaxis, by drugs and surgical procedures. Studies in animal…
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1984
1984
Studies on histaminergic compounds. II: Synthesis and histamine H2-activity of dimaprit and some of its analogues
G. Sterk
,
H. Goot
,
H. Timmerman
1984
Corpus ID: 89354424
Synthese du dimaprit (S-[dimethylamino-3 propyl] thiocarbamimidate) et de derives N 1 et N 2 -substitues. Etude de leur activite…
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1984
1984
Macrocyclic polyamines as a possible chemical model for histamine H2-receptors.
E. Kimura
,
T. Koike
,
M. Kodama
Chemical and pharmaceutical bulletin
1984
Corpus ID: 45174759
An 18-membered macrocyclic hexaamine, [18] aneN6, interacts with histamine and its H2-agonist dimaprit at physiological pH to…
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1983
1983
Histamine-induced prolactin release: pharmacological characterization of receptors in male rats.
A. Donoso
,
M. B. Zárate
,
A. Seltzer
Neuroendocrinology
1983
Corpus ID: 25861128
Studies were undertaken to investigate the nature of receptors involved in the prolactin-releasing action of histamine in male…
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1979
1979
The nature of the receptor mediating stimulant effects of histamine on rapidly adapting vagal afferents in the lungs.
S. Sampson
,
E. Vidruk
Journal of Physiology
1979
Corpus ID: 20720813
1. The effects of histamine H1‐ and H2‐agonists on these airway sensory receptors were also examined. 2. Neither I.V. infusion of…
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1979
1979
Dual histamine receptor mechanism in guinea-pig lung.
N. Chand
,
L. Deroth
Pharmacology
1979
Corpus ID: 46852879
Isolated guinea-pig lung parenchymal strips (GPLS) relaxed in response to the selective histamine H2-receptor agonists, dimaprit…
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1978
1978
Human lung tissue and anaphylaxis: the effects of histamine on the immunologic release of mediators.
M. Kaliner
American Review of Respiratory Disease
1978
Corpus ID: 33047228
The IgE-mediated, antigen-induced release of histamine from human lung tissue causes profound changes in lung cyclic adenosine…
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1977
1977
Dimaprit, [S-[3-(N,N-dimethylamino)propyl]isothiourea]. A highly specific histamine H2-receptor agonist. Part 2. Structure-activity considerations
G. J. Durant
,
C. Ganellin
,
M. Parsons
Agents and Actions
1977
Corpus ID: 7303170
Dimaprit, S-[3-(N,N-dimethylamino)propyl]isothiourea, appears to be a highly specific histamine H2-receptor agonist. Further…
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