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Chromosomal microarray (CMA) is increasingly utilized for genetic testing of individuals with unexplained developmental delay… Expand The results of many clinical tests are quantitative and are provided on a continuous scale. To help decide the presence or… Expand Many questions in medical research are investigated in observational studies (1). Much of the research into the cause of diseases… Expand BACKGROUND AND OBJECTIVE
Publication bias and other sample size effects are issues for meta-analyses of test accuracy, as for… Expand SUMMARY Malaria presents a diagnostic challenge to laboratories in most countries. Endemic malaria, population movements, and… Expand We review the principles and practical application of receiver-operating characteristic (ROC) analysis for diagnostic tests. ROC… Expand CONTEXT
The literature contains a large number of potential biases in the evaluation of diagnostic tests. Strict application of… Expand The simplest diagnostic test is one where the results of an investigation, such as an x ray examination or biopsy, are used to… Expand Background and Purpose The etiology of ischemic stroke affects prognosis, outcome, and management. Trials of therapies for… Expand To determine why many diagnostic tests have proved to be valueless after optimistic introduction into medical practice, we… Expand