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Dexamethasone

Known as: dexamethasone (DMX), 1-Dehydro-16?-methyl-9?-fluorohydrocortisone, 1-Dehydro-16alpha-methyl-9alpha-fluorohydrocortisone 
A synthetic adrenal corticosteroid with potent anti-inflammatory properties. In addition to binding to specific nuclear steroid receptors… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
Exosomes are nano-sized biovesicles released into surrounding body fluids upon fusion of multivesicular bodies and the plasma… Expand
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Review
2019
Review
2019
BACKGROUND Selinexor, a selective inhibitor of nuclear export compound that blocks exportin 1 (XPO1) and forces nuclear… Expand
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Highly Cited
2016
Highly Cited
2016
BACKGROUND Daratumumab, a human IgGκ monoclonal antibody that targets CD38, induces direct and indirect antimyeloma activity and… Expand
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Highly Cited
2016
Highly Cited
2016
BACKGROUND Daratumumab showed promising efficacy alone and with lenalidomide and dexamethasone in a phase 1-2 study involving… Expand
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Highly Cited
2015
Highly Cited
2015
BACKGROUND Lenalidomide plus dexamethasone is a reference treatment for relapsed multiple myeloma. The combination of the… Expand
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Highly Cited
2010
Highly Cited
2010
BACKGROUND High-dose dexamethasone is a mainstay of therapy for multiple myeloma. We studied whether low-dose dexamethasone in… Expand
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Highly Cited
2007
Highly Cited
2007
BACKGROUND Lenalidomide is a structural analogue of thalidomide with similar but more potent biologic activity. This phase 3… Expand
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Highly Cited
2007
Highly Cited
2007
BACKGROUND Lenalidomide, an oral immunomodulatory drug that is similar to thalidomide but has a different safety profile, has… Expand
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Highly Cited
2006
Highly Cited
2006
PURPOSE To determine if thalidomide plus dexamethasone yields superior response rates compared with dexamethasone alone as… Expand
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Highly Cited
2005
Highly Cited
2005
BACKGROUND This study compared bortezomib with high-dose dexamethasone in patients with relapsed multiple myeloma who had… Expand
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