Dexamethasone

Known as: dexamethasone (DMX), 1-Dehydro-16?-methyl-9?-fluorohydrocortisone, 1-Dehydro-16alpha-methyl-9alpha-fluorohydrocortisone 
A synthetic adrenal corticosteroid with potent anti-inflammatory properties. In addition to binding to specific nuclear steroid receptors… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1949-2018
01000200019492017

Papers overview

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Highly Cited
2015
Highly Cited
2015
BACKGROUND Lenalidomide plus dexamethasone is a reference treatment for relapsed multiple myeloma. The combination of the… (More)
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Highly Cited
2010
Highly Cited
2010
BACKGROUND High-dose dexamethasone is a mainstay of therapy for multiple myeloma. We studied whether low-dose dexamethasone in… (More)
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Highly Cited
2010
Highly Cited
2010
This phase 1/2 study is the first prospective evaluation of lenalidomide-bortezomib-dexamethasone in front-line myeloma. Patients… (More)
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Highly Cited
2010
Highly Cited
2010
BACKGROUND Thalidomide plus dexamethasone (TD) is a standard induction therapy for myeloma. We aimed to assess the efficacy and… (More)
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Highly Cited
2007
Highly Cited
2007
BACKGROUND Lenalidomide is a structural analogue of thalidomide with similar but more potent biologic activity. This phase 3… (More)
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Highly Cited
2007
Highly Cited
2007
BACKGROUND Lenalidomide, an oral immunomodulatory drug that is similar to thalidomide but has a different safety profile, has… (More)
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Highly Cited
2006
Highly Cited
2006
PURPOSE To determine if thalidomide plus dexamethasone yields superior response rates compared with dexamethasone alone as… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND This study compared bortezomib with high-dose dexamethasone in patients with relapsed multiple myeloma who had… (More)
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Highly Cited
2005
Highly Cited
2005
We report the results of a phase 2 trial using lenalidomide plus dexamethasone (Rev/Dex) as initial therapy for myeloma. Thirty… (More)
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Highly Cited
1996
Highly Cited
1996
BACKGROUND Mortality and morbidity rates are high among adults with acute bacterial meningitis, especially those with… (More)
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