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Demeclocycline

Known as: Demeclociclina, 7-Chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-1,11-dioxo-2-naphthacenecarboxamide, 6-Demethyl-7-chlorotetracycline 
A semi-synthetic, broad-spectrum naphthacene antibiotic produced by the bacterium Streptomyces aureofaciens. Demeclocycline binds to bacterial 30S… 
National Institutes of Health

Related topics

Related topics

28 relations
Acne VulgarisBacterial InfectionsDecreased Protein Synthesis [PE]Demeclocycline:MCnc:Pt:Ser/Plas:Qn

Broader (1)

Anti-Bacterial Agents

Narrower (4)

DeclomycinDemeclocycline HydrochlorideLedermixdeteclo

Papers overview

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Highly Cited
1997
Highly Cited
1997
Evaluation of amperometric detection for the liquid-chromatographic determination of tetracycline antibiotics and their common contaminants in pharmaceutical formulations.
Highly Cited
1969
Highly Cited
1969
Systemic allergic reactions to ingested antigens.
Review
1969
Review
1969
Applications of modern electroanalytical techniques to pharmaceutical chemistry.
0 The apparent partition coefficients between n-octyl alcohol and aqueous buffers (ranging from pH 2.1 to 8.5) were determined… 
Highly Cited
1969
Highly Cited
1969
Effects of systemic demethylchlortetracycline on human cutaneous microflora.
The aerobic flora of the axilla and forehead of 20 normal human subjects was studied through a 3-week course of 600 mg of… 
Highly Cited
1968
Highly Cited
1968
Photosensitivity studies with demethylchlortetracycline and doxycycline.
Of 30 volunteers, ten were given demethylchlortetracycline (600 mg/day), ten, doxycycline (200 mg/day), and ten, a placebo, for… 
Highly Cited
1966
Highly Cited
1966
Objective evaluation of demethylchlortetracycline hydrochloride in the treatment of acne.
Ninety-four patients with inflammatory acne were treated with demethylchlortetracycline hydrochloride in a doubleblind, modified… 
Highly Cited
1963
Highly Cited
1963
DOUBLE-BLIND STUDY OF PREMATURE RUPTURE OF THE MEMBRANES. A REPORT OF 1,896 CASES.
Highly Cited
1961
Highly Cited
1961
Photosensitivity and photo-onycholysis due to demethylchlortetracycline.
During the past 2 years a new compound, demethylchlortetracycline (Declomycin), * hereafter referred to as DMCT, has found wide… 
Highly Cited
1961
Highly Cited
1961
Respiratory disease in volunteers infected with Eaton agent: a preliminary report.
Recent epidemiologic studies have provided evidence that the filterable agent first described by Eaton in 1944 was associated… 
1960
1960
Tetracycline resistance of group A beta hemolytic streptococci.
This study was undertaken to determine whether any group A streptococci isolated from clinical sources are now resistant to… 
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