Demeclocycline

Known as: Demeclociclina, 7-Chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-1,11-dioxo-2-naphthacenecarboxamide, 6-Demethyl-7-chlorotetracycline 
A semi-synthetic, broad-spectrum naphthacene antibiotic produced by the bacterium Streptomyces aureofaciens. Demeclocycline binds to bacterial 30S… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1957-2018
0102019572017

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
Poly(ADP-ribose) polymerase-1 (PARP-1), when activated by DNA damage, promotes both cell death and inflammation. Here we report… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2005
2005
Minocycline is a potent neuroprotective tetracycline in animal models of cerebral ischemia. We examined the protective properties… (More)
Is this relevant?
1992
1992
Continuation of net periosteal bone gain after cessation of longitudinal growth has been inferred from sequential radiographic… (More)
Is this relevant?
1985
1985
A series of studies was previously devoted to the dependence of the bioavailability of various tetracyclines on their… (More)
  • table 1
  • table 2
  • figure 1
  • figure 2
  • figure 3
Is this relevant?
1981
1981
Seventeen patients with cancer or aplastic anemia received demeclocycline as treatment for hyponatremia. Prior to demeclocycline… (More)
Is this relevant?
1980
1980
In five hyponatremic, cirrhotic patients, demeclocycline hydrochloride was used to inhibit the hydroosmotic effect of vasopressin… (More)
Is this relevant?
1978
1978
We evaluated demeclocycline and lithium therapy in 10 patients with the syndrome of inappropriate secretion of antidiuretic… (More)
Is this relevant?
1977
1977
Three patients with cirrhosis, ascites, and dilutional hyponatremia were treated with demeclocycline in an attempt to correct the… (More)
Is this relevant?
1975
1975
We have studied the effects of demeclocycline on the water metabolism of a patient with the syndrome of inappropriate… (More)
Is this relevant?
1975
1975
Antimicrobials are used emperically in a variety of inflammatory dermatoses such as rosacea and dermatitis herpetiformis… (More)
Is this relevant?