Delapril Hydrochloride

The hydrochloride salt of delapril, a lipophilic, non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. As a… Expand
National Institutes of Health

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delapril

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2009
2009
G006 Réduction des troubles de conduction et des arythmies ventriculaires par un IEC dans un modèle murin d’insuffisance cardiaque
Les effets benefiques des inhibiteurs de l’enzyme de conversion de l’angiotensine (IEC) sur la mortalite, la morbidite et la… Expand
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2003
2003
Single oral dose pharmacokinetic interaction study of manidipine and delapril in healthy volunteers.
OBJECTIVE The objective of the study was to assess potential pharmacokinetic interactions between delapril, an angiotensin… Expand
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2003
2003
Angiotensin II type 2 receptor inhibits prorenin processing in juxtaglomerular cells.
Long-term treatment with an angiotensin II type 1 receptor blocker (ARB) has been shown to decrease the plasma renin activity… Expand
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2003
2003
Pharmacokinetics and tolerability of a new manidipine and delapril fixed oral combination in young and elderly subjects.
OBJECTIVES The aim of the present study was to compare the pharmacokinetic and pharmacodynamic properties of a fixed combination… Expand
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2000
2000
Delapril versus manidipine in hypertensive therapy to halt the type-2-diabetes-mellitus-associated nephropathy.
Thirty-nine hypertensive patients with type 2 diabetes mellitus were followed under long-term treatment (mean, 20.7 months) with… Expand
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1998
1998
Long-term effects of delapril hydrochloride on procollagen type III amino-terminal peptide, left ventricular mass and left ventricular function in hypertensive patients.
The long-term effect of delapril hydrochloride, a non-sulfhydryl angiotensin converting enzyme inhibitor, on serum concentrations… Expand
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1994
1994
Anti-hypertensive effect of oral controlled-release microspheres containing an ACE inhibitor (delapril hydrochloride) in rats.
An oral controlled-release drug delivery system based on microspheres of polyglycerol esters of fatty acids (PGEFs), was applied… Expand
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1994
1994
Effects of delapril hydrochloride on the myocardium of spontaneously hypertensive rats.
OBJECTIVE To investigate the effects of long term treatment with delapril hydrochloride (an angiotensin-converting enzyme… Expand
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1992
1992
Renal and extra-renal renin gene expression in spontaneously hypertensive rats.
To study the effect of antihypertensive therapy on the regulation of renin gene expression, the levels of tissue renin messenger… Expand
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1987
1987
Pharmacokinetics and acute effect on the renin-angiotensin system of delapril in patients with chronic renal failure.
The acute effect on the renin-angiotensin system and the pharmacokinetic properties of delapril, a new angiotensin converting… Expand
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