De novo transcriptome assembly

We describe the design and implementation of Open vSwitch, a multi-layer, open source virtual switch for all major hypervisor… Expand

In this thesis, a de novo transcriptome assembler was implemented based on the overlap-layout-consensus paradigm. It was written… Expand

Epileptic encephalopathies are a devastating group of severe childhood epilepsy disorders for which the cause is often unknown… Expand

As more genomes are assembled from scratch, scientists are struggling to assess and improve their quality. 

Brian J. O’Roak, Pelagia Deriziotis, Choli Lee, Laura Vives, Jerrod J. Schwartz, Santhosh Girirajan, Emre Karakoc, Alexandra P… Expand

Motivation: An important step of "metagenomics" analysis is the assembly of multiple genomes from mixed sequence reads of… Expand

The megacities arising around the planet are like the Internet where many events are taking place simultaneously. The urban scape… Expand

Cell-to-cell communication is a crucial prerequisite for the development and maintenance of multicellular organisms. To date… Expand

Set on its current course thirty years ago by Herbert Simon's notions of bounded rationality and sequential stages, the research… Expand

Within thirty years, we will have the technological means to create superhuman intelligence. Shortly after, the human era will be… Expand