FAQ

DYRK1B gene

Known as: dual specificity tyrosine phosphorylation regulated kinase 1B, DUAL-SPECIFICITY TYROSINE PHOSPHORYLATION-REGULATED KINASE 1B, DYRK1B 
 

Topic mentions per year

Topic mentions per year

1993-2017
024619932017

Papers overview

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2016
2016
Iron-induced oxidative stress activates AKT and ERK1/2 and decreases Dyrk1B and PRMT1 in neuroblastoma SH-SY5Y cells.
Iron is essential for proper neuronal functioning; however, excessive accumulation of brain iron is reported in Parkinson's… (More)
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2016
2016
DYRK1B as therapeutic target in Hedgehog/GLI-dependent cancer cells with Smoothened inhibitor resistance.
A wide range of human malignancies displays aberrant activation of Hedgehog (HH)/GLI signaling, including cancers of the skin… (More)
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2015
2015
The Tumor Suppressor NKX3.1 Is Targeted for Degradation by DYRK1B Kinase.
UNLABELLED NKX3.1 is a prostate-specific homeodomain protein and tumor suppressor whose expression is reduced in the earliest… (More)
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2015
2015
Role of dual specificity tyrosine-phosphorylation-regulated kinase 1B (Dyrk1B) in S-phase entry of HPV E7 expressing cells from quiescence.
The high-risk human papillomavirus (HPV) is the causative agent for cervical cancer. The HPV E7 oncogene promotes S-phase entry… (More)
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2015
2015
Identification of DYRK1B as a substrate of ERK1/2 and characterisation of the kinase activity of DYRK1B mutants from cancer and metabolic syndrome
The dual-specificity tyrosine-phosphorylation-regulated kinase, DYRK1B, is expressed de novo during myogenesis, amplified or… (More)
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2014
2014
A novel DYRK1B inhibitor AZ191 demonstrates that DYRK1B acts independently of GSK3β to phosphorylate cyclin D1 at Thr(286), not Thr(288).
DYRK1B (dual-specificity tyrosine phosphorylation-regulated kinase 1B) is amplified in certain cancers and may be an oncogene… (More)
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2011
2011
A K+ channel from salt-tolerant melon inhibited by Na+.
• The possible roles of K(+) channels in plant adaptation to high Na(+) conditions have not been extensively analyzed. Here, we… (More)
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Highly Cited
2009
Highly Cited
2009
Harmine specifically inhibits protein kinase DYRK1A and interferes with neurite formation.
DYRK1A is a dual-specificity protein kinase that autophosphorylates a conserved tyrosine residue in the activation loop but… (More)
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1999
1999
Cloning and characterization of DYRK1B, a novel member of the DYRK family of protein kinases.
The DYRK1A gene on human chromosome 21 encodes a protein kinase presumed to be involved in the pathogenesis of mental retardation… (More)
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1993
1993
A Runge - Kutta Type Boundary Value ODE Solverwith Defect
A popular approach for the numerical solution of boundary value ODE problems involves the use of collocation methods. Such… (More)
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