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DTX3L gene

Known as: BBAP, DTX3L, rhysin 2 
 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
LIPG signaling promotes tumor initiation and metastasis of human basal-like triple-negative breast cancer
Current understanding of aggressive human basal-like triple-negative breast cancer (TNBC) remains incomplete. In this study, we… Expand
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Highly Cited
2017
Highly Cited
2017
Ubiquitin Modification by the E3 Ligase/ADP-Ribosyltransferase Dtx3L/Parp9.
ADP-ribosylation of proteins is emerging as an important regulatory mechanism. Depending on the family member, ADP… Expand
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Highly Cited
2017
Highly Cited
2017
Laminar flow downregulates Notch activity to promote lymphatic sprouting
The major function of the lymphatic system is to drain interstitial fluid from tissue. Functional drainage causes increased fluid… Expand
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2015
2015
Deltex-3-like (DTX3L) stimulates metastasis of melanoma through FAK/PI3K/AKT but not MEK/ERK pathway
Deltex-3-like (DTX3L), an E3 ligase, is a member of the Deltex (DTX) family and is also called B-lymphoma and BAL-associated… Expand
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2014
2014
DTX3L and ARTD9 inhibit IRF1 expression and mediate in cooperation with ARTD8 survival and proliferation of metastatic prostate cancer cells
BackgroundProstate cancer (PCa) is one of the leading causes of cancer-related mortality and morbidity in the aging male… Expand
Highly Cited
2012
Highly Cited
2012
BAL1 and Its Partner E3 Ligase, BBAP, Link Poly(ADP-Ribose) Activation, Ubiquitylation, and Double-Strand DNA Repair Independent of ATM, MDC1, and RNF8
ABSTRACT The BAL1 macrodomain-containing protein and its partner E3 ligase, BBAP, are overexpressed in chemotherapy-resistant… Expand
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Highly Cited
2009
Highly Cited
2009
BBAP monoubiquitylates histone H4 at lysine 91 and selectively modulates the DNA damage response.
Although the BBAP E3 ligase and its binding partner BAL are overexpressed in chemotherapy-resistant lymphomas, the role of these… Expand
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2008
2008
The macroPARP genes parp‐9 and parp‐14 are developmentally and differentially regulated in mouse tissues
The macroPARPs Parp‐9 and Parp‐14 are macro domain containing poly(ADP‐ribose) polymerases involved in transcriptional regulation… Expand
Highly Cited
2006
Highly Cited
2006
BAL1 and BBAP Are Regulated by a Gamma Interferon-Responsive Bidirectional Promoter and Are Overexpressed in Diffuse Large B-Cell Lymphomas with a Prominent Inflammatory Infiltrate
ABSTRACT BAL1 is a transcription modulator that is overexpressed in chemoresistant, diffuse large B-cell lymphomas (DLBCLs). BAL1… Expand
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Highly Cited
2003
Highly Cited
2003
The BAL-binding Protein BBAP and Related Deltex Family Members Exhibit Ubiquitin-Protein Isopeptide Ligase Activity*
Members of the DTX (Deltex) family act as Notch signaling modifiers and may also regulate transcription through interactions with… Expand
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