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DSG2 gene

Known as: DESMOGLEIN 2, DSG2, CDHF5 
National Institutes of Health

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desmoglein 2

Papers overview

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2018
2018
Therapeutic and prophylactic gastrectomy in a family with hereditary diffuse gastric cancer secondary to a CDH1 mutation: a case series
BackgroundGastric cancer is the fifth most prevalent and the third most lethal cancer worldwide, causing approximately 720,000… 
2014
2014
Complementary molecular approaches reveal heterogeneous CDH1 germline defects in Italian patients with hereditary diffuse gastric cancer (HDGC) syndrome
Germline inactivation of the E‐cadherin gene (CDH1) is associated with hereditary diffuse gastric cancer (HDGC), a rare autosomal… 
2014
2014
Presymptomatic Identification of CDH1 Germline Mutation in a Healthy Korean Individual with Family History of Gastric Cancer
Gastric cancer (GC) is one of the most common cancers with high morbidity and mortality. Familial GC is seen in 10% of cases, and… 
2011
2011
ADP-Ribosylation Factor 6 Mediates E-Cadherin Recovery by Chemical Chaperones
E-cadherin plays a powerful tumor suppressor role. Germline E-cadherin mutations justify 30% of Hereditary Diffuse Gastric Cancer… 
2010
2010
Germline mutation of the E-cadherin gene in three sibling cases with advanced gastric cancer: clinical consequences for the other family members
Background and aims Germline mutations in the E-cadherin (CDH1) gene have been found in families with hereditary diffuse gastric… 
Review
2010
Review
2010
Arrhythmogenic right ventricular cardiomyopathy is a disease of cardiac stem cells
Purpose To review recent developments in clinical aspects, molecular genetics and pathogenesis of arrhythmogenic right… 
2010
2010
A novel truncating mutation in the E-cadherin gene in the first Iranian family with hereditary diffuse gastric cancer.
Review
2008
Review
2008
Hereditary diffuse gastric cancer: prophylactic surgical oncology implications.
2000
2000
The amino- and carboxyl-terminal tails of (beta)-catenin reduce its affinity for desmoglein 2.
beta-catenin and plakoglobin are members of the armadillo family of proteins and were first identified as components of… 
2000
2000
Expression of a single pair of desmosomal glycoproteins renders the corneal epithelium unique amongst stratified epithelia.
PURPOSE To determine desmosomal glycoprotein isoform expression in bovine corneal, limbal, and conjunctival epithelium and… 
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