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DSG2 gene

Known as: DESMOGLEIN 2, DSG2, CDHF5 
 
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
IMPORTANCE E-cadherin (CDH1) is a cancer predisposition gene mutated in families meeting clinically defined hereditary diffuse… Expand
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Highly Cited
2010
Highly Cited
2010
Hereditary diffuse gastric cancer (HDGC) is an autosomal dominant cancer susceptibility syndrome characterized by early-onset… Expand
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Highly Cited
2009
Highly Cited
2009
Germline CDH1 point or small frameshift mutations can be identified in 30–50% of hereditary diffuse gastric cancer (HDGC… Expand
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Highly Cited
2009
Highly Cited
2009
BACKGROUND & AIMS Hereditary diffuse gastric cancer (HDGC) families carry CDH1 heterozygous germline mutations; their tumors… Expand
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Highly Cited
2008
Highly Cited
2008
A subset of patients with diffuse gastric cancer harbor deleterious cancer‐causing germline mutations in the type 1 E‐cadherin… Expand
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Highly Cited
2004
Highly Cited
2004
Approximately 30% of all hereditary diffuse gastric cancer (HDGC) families carry CDH1 germline mutations. The other two thirds… Expand
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Highly Cited
2002
Highly Cited
2002
The International Gastric Cancer Linkage Consortium (IGCLC) predicted that up to 25% of families fulfilling the criteria for… Expand
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Highly Cited
2001
Highly Cited
2001
BACKGROUND & AIMS Germline mutations in CDH1 are known to cause hereditary diffuse gastric cancer (HDGC). Breast and colorectal… Expand
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Highly Cited
1994
Highly Cited
1994
Desmosomes are junctions between epithelial, myocardiac, and certain other kinds of cells. They represent plasma membrane domains… Expand
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Highly Cited
1993
Highly Cited
1993
Desmosomal junctions are abundant in epidermis and contain two classes of transmembrane glycoprotein, the desmocollins and the… Expand
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