DSG2 gene

Known as: DESMOGLEIN 2, DSG2, CDHF5 
 
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
IMPORTANCE E-cadherin (CDH1) is a cancer predisposition gene mutated in families meeting clinically defined hereditary diffuse… (More)
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2013
2013
Diffuse gastric cancers typically present as late-stage tumours and, as a result, the 5 year survival rate is poor. Some gastric… (More)
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2010
2010
CD44 is the major ubiquitously expressed cell surface receptor for hyaluronate. The CD44 gene encodes several protein isoforms… (More)
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Highly Cited
2009
Highly Cited
2009
Germline CDH1 point or small frameshift mutations can be identified in 30-50% of hereditary diffuse gastric cancer (HDGC… (More)
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Highly Cited
2009
Highly Cited
2009
BACKGROUND & AIMS Hereditary diffuse gastric cancer (HDGC) families carry CDH1 heterozygous germline mutations; their tumors… (More)
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Highly Cited
2008
Highly Cited
2008
Around 25-40% of cases of hereditary diffuse gastric cancer (HDGC) are caused by heterozygous E-cadherin (CDH1) germline… (More)
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2007
2007
Hereditary diffuse gastric cancer (HDGC) is a cancer predisposition syndrome caused by germline mutation of the gene encoding the… (More)
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Highly Cited
2002
Highly Cited
2002
The International Gastric Cancer Linkage Consortium (IGCLC) predicted that up to 25% of families fulfilling the criteria for… (More)
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Highly Cited
2001
Highly Cited
2001
BACKGROUND & AIMS Germline mutations in CDH1 are known to cause hereditary diffuse gastric cancer (HDGC). Breast and colorectal… (More)
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Highly Cited
1994
Highly Cited
1994
Desmosomes are junctions between epithelial, myocardiac, and certain other kinds of cells. They represent plasma membrane domains… (More)
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