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DS-5565

National Institutes of Health

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Broader (1)

mirogabalin

Papers overview

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2018
2018
Target : Calcium Channel Pathway : Membrane Transporter / Ion Channel Solubility : DMSO : 10 mM
  • 2018
  • Corpus ID: 49231483
BIOLOGICAL ACTIVITY: Mirogabalin (DS-5565) is a novel, preferentially selective α2δ-1 ligand characterized by high potency and… 
2016
2016
Exposure–response modeling of average daily pain score, and dizziness and somnolence, for mirogabalin (DS‐5565) in patients with diabetic peripheral neuropathic pain
Mirogabalin (DS‐5565) is an α2δ‐1 ligand being developed for pain associated with diabetic peripheral neuropathy, fibromyalgia… 
2014
2014
Pharmacological, Pharmacokinetics and Safety Profiles of DS-5565, a Novel α 2 δ Ligand (P7.301)
OBJECTIVE: To clarify the characteristics of DS-5565 as a novel α 2 δ ligand , we conducted the experiments using pregabalin (PGB… 
2014
2014
DS-5565 for the Treatment Of Diabetic Peripheral Neuropathic Pain: Randomized, Double-Blind, Placebo- And Active Comparator-Controlled Phase II Study (I6-1.007)
OBJECTIVE: To identify a dose(s) of DS-5565 with meaningful clinical efficacy and manageable side effects for treatment of… 
2014
2014
Pharmacokinetics of DS-5565, a Novel α 2 δ Ligand, in Rats and Monkeys, and Assessment of DDI Risk (P7.313)
OBJECTIVE: We elucidated the pharmacokinetic profiles of DS-5565 in animals and drug interaction risk as perpetrator. BACKGROUND… 
2014
2014
Central Nervous System Safety And Tolerability Of DS-5565: A Randomized, Double-Blind, Placebo- And Active Comparator-Controlled Phase II Study In Diabetic Peripheral Neuropathic Pain (P7.296)
OBJECTIVE: To profile CNS safety/tolerability of DS-5565 (a potent, specific alpha2-delta ligand) in diabetic peripheral… 
2013
2013
Pharmacokinetics of DS-5565, a novel α2δ ligand, in rats and monkeys and assessment of DDI risk
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