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DPY19L2 gene

Known as: dpy-19 like 2 (C. elegans), spermatogenesis associated 34, DPY19-LIKE 2 
National Institutes of Health

Papers overview

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2018
2018
Globozoospermia is characterized by the presence of 100% acrosomeless round-headed spermatozoa in an ejaculate. Failed… Expand
2015
2015
We recently identified the DPY19L2 gene as the main genetic cause of human globozoospermia. Non-genetically characterized cases… Expand
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Review
2015
Review
2015
BACKGROUND Male infertility affects >20 million men worldwide and represents a major health concern. Although multifactorial… Expand
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2013
2013
Globozoospermia, characterized by round-headed spermatozoa without acrosomes, is a rare and severe teratozoospermia causing… Expand
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Highly Cited
2013
Highly Cited
2013
STUDY QUESTION Does DPY19L2 status influence intracytoplasmic sperm injection (ICSI) outcomes with or without assisted oocyte… Expand
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Highly Cited
2012
Highly Cited
2012
Sperm-head elongation and acrosome formation, which take place during the last stages of spermatogenesis, are essential to… Expand
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Highly Cited
2012
Highly Cited
2012
To date, mutations in two genes, SPATA16 and DPY19L2, have been identified as responsible for a severe teratozoospermia, namely… Expand
Highly Cited
2012
Highly Cited
2012
STUDY QUESTION Do DPY19L2 heterozygous deletions and point mutations account for some cases of globozoospermia? SUMMARY ANSWER… Expand
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Highly Cited
2011
Highly Cited
2011
An increasing number of couples require medical assistance to achieve a pregnancy, and more than 2% of the births in Western… Expand
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Highly Cited
2011
Highly Cited
2011
Globozoospermia, characterized by round-headed spermatozoa, is a rare (< 0.1% in male infertile patients) and severe… Expand