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DPY19L2 gene

Known as: dpy-19 like 2 (C. elegans), spermatogenesis associated 34, DPY19-LIKE 2 
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
We recently identified the DPY19L2 gene as the main genetic cause of human globozoospermia. Non-genetically characterized cases… 
Review
2015
Review
2015
BACKGROUND Male infertility affects >20 million men worldwide and represents a major health concern. Although multifactorial… 
2013
2013
Globozoospermia, characterized by round-headed spermatozoa without acrosomes, is a rare and severe teratozoospermia causing… 
Highly Cited
2013
Highly Cited
2013
STUDY QUESTION Does DPY19L2 status influence intracytoplasmic sperm injection (ICSI) outcomes with or without assisted oocyte… 
Highly Cited
2012
Highly Cited
2012
To date, mutations in two genes, SPATA16 and DPY19L2, have been identified as responsible for a severe teratozoospermia, namely… 
Highly Cited
2012
Highly Cited
2012
Sperm-head elongation and acrosome formation, which take place during the last stages of spermatogenesis, are essential to… 
Highly Cited
2012
Highly Cited
2012
STUDY QUESTION Do DPY19L2 heterozygous deletions and point mutations account for some cases of globozoospermia? SUMMARY ANSWER… 
Highly Cited
2011
Highly Cited
2011
Highly Cited
2011
2006
2006
BackgroundLow copy repeats (LCRs) are thought to play an important role in recent gene evolution, especially when they facilitate…