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DPP4 protein, human

Known as: DPP-IV protein, human, EC 3.4.14.5, Dipeptidyl Peptidase IV 
Dipeptidyl peptidase 4 (766 aa, ~88 kDa) is encoded by the human DPP4 gene. This protein is involved in proteolytic regulation of T cell activation.
National Institutes of Health

Related topics

Related topics

10 relations
Cell-Cell Adhesion ProcessDPP4 geneEnzyme GeneHomo sapiens

Broader (1)

Dipeptidyl-Peptidase IV

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Saxagliptin and Tadalafil Differentially Alter Cyclic Guanosine Monophosphate (cGMP) Signaling and Left Ventricular Function in Aortic‐Banded Mini‐Swine
Background Cyclic guanosine monophosphate‐protein kinase G‐phosphodiesterase 5 signaling may be disturbed in heart failure (HF… 
Highly Cited
2013
Highly Cited
2013
New Alkylfuranyl-Substituted Benzo[1,2-b:4,5-b′]dithiophene-Based Donor–Acceptor Polymers for Highly Efficient Solar Cells
Two new alkylfuranyl-substituted conjugated donor–acceptor polymers—PBDTF-DPP and PBDTF-DPPF—were designed and synthesized. To… 
2009
2009
Increased plasma dipeptidyl peptidase IV (DPP IV) activity and decreased DPP IV activity of visceral but not subcutaneous adipose tissue in impaired glucose tolerance rats induced by high-fat or high…
Several studies have investigated whether dipeptidyl peptidase IV (DPP IV) activity is correlated to the severity of diabetes… 
Highly Cited
2006
Highly Cited
2006
Capture of phosphorus(I) and arsenic(I) moieties by a 1,2-bis(arylimino)acenaphthene (aryl-BIAN) ligand. A case of intramolecular charge transfer.
The reaction of PCl3 with SnCl2 in THF solution, followed by treatment with dpp-BIAN (dpp = 2,6-i-Pr2C6H3), affords the… 
Highly Cited
2002
Highly Cited
2002
Dipeptidyl peptidase IV inhibition improves impaired glucose tolerance in high-fat diet-fed rats: study using a Fischer 344 rat substrain deficient in its enzyme activity.
This study was performed to determine the effects of a high-fat diet on glucose metabolism after an oral glucose challenge in… 
Highly Cited
1997
Highly Cited
1997
A prediction of DPP IV/CD26 domain structure from a physico-chemical investigation of dipeptidyl peptidase IV (CD26) from human seminal plasma.
1995
1995
Costimulation of CD4+ and CD8+ T cells through CD26: The ADA‐binding epitope is not essential for complete signaling
It was previously shown that CD26 (DPP IV, EC 3.4.14.5) is a binding site for adenosine deaminase (ADA, EC 3.5.4.4) on T cells… 
1993
1993
Function of dipeptidyl peptidase IV (CD26, Tp103) in transfected human T cells.
CD26 (Tp103) is a proteolytic enzyme (dipeptidyl peptidase IV) expressed on the T cell surface that defines an alternative… 
Highly Cited
1989
Highly Cited
1989
Primary structure of rat liver dipeptidyl peptidase IV deduced from its cDNA and identification of the NH2-terminal signal sequence as the membrane-anchoring domain.
1983
1983
Purification and properties of dipeptidyl peptidase II from rat kidney.
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