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DPI 3290

Known as: DPI-3290, DPI3290 
National Institutes of Health

Papers overview

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2017
2017
The opioid receptor triple agonist DPI-125 produces analgesia with less respiratory depression and reduced abuse liability
Opioid analgesics remain the first choice for the treatment of moderate to severe pain, but they are also notorious for their… 
2013
2013
二芳基甲基哌嗪阿片受体激动剂DPI-3290的合成方法研究 Practical synthesis of benzhydrylpiperazine opioid receptor agonist DPI-3290 云南民族大学学报：自然科学版，2013，22（4）：242-245
报道了二芳基甲基哌嗪阿片受体激动剂DPI-3290的一种新的合成路线.该合成的关键步骤是一个四组分三步串联反应，通过对这一反应的条件和操作的优化，以41%的较好产率得到了预期产物.应用这一路线，以四步直线步骤和16.8%的总产率实现了DPI-3290… 
2003
2003
DPI-3290 [(+)-3-((α-R)-α-((2S,5R)-4-Allyl-2,5-dimethyl-1-piperazinyl)-3-hydroxybenzyl)-N-(3-fluorophenyl)-N-methylbenzamide]. II. A Mixed Opioid Agonist with Potent Antinociceptive Activity and…
Allyl-2,5-dimethyl-1-piperazines have been of interest as analgesic agents for the management of moderate-to-severe pain. In this… 
2003
2003
DPI-3290 [(+)-3-((alpha-R)-alpha-((2S,5R)-4-allyl-2,5-dimethyl-1-piperazinyl)-3-hydroxybenzyl)-N-(3-fluorophenyl)-N-methylbenzamide]. I. A mixed opioid agonist with potent antinociceptive activity.
Compound (+)-3-((alpha-R)-alpha-((2S,5R)-4-allyl-2,5-dimethyl-1-piperazinyl)-3-hydroxybenzyl)-N-(3-fluorophenyl)-N… 
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