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DPH2 gene

Known as: DPH2, DPH2L2, DPH2 homolog 
National Institutes of Health

Papers overview

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2019
2019
Forward genetic screen in human podocytes identifies diphthamide biosynthesis genes as regulators of adhesion.
Background: Podocyte function is tightly linked to the complex organization of its cytoskeleton, and adhesion to the underlying… 
2014
2014
Genetic Modifiers of Neurofibromatosis Type 1-Associated Café-au-Lait Macule Count Identified Using Multi-platform Analysis
Neurofibromatosis type 1 (NF1) is an autosomal dominant, monogenic disorder of dysregulated neurocutaneous tissue growth… 
2013
2013
Equilibrium Distributions of Discrete Phase Type
It is well known that the family of discrete phase-type distributions is closed under convolutions, mixtures, and the unary… 
2010
2010
Diphthamide biosynthesis requires an Fe-S enzyme-generated organic radical
Summary Archaeal and eukaryotic translation elongation factor 2 contain a unique posttranslationally modified histidine residue… 
2010
2010
A Dominant-Negative Approach That Prevents Diphthamide Formation Confers Resistance to Pseudomonas Exotoxin A and Diphtheria Toxin
Diphtheria toxin (DT), Pseudomonas aeruginosa Exotoxin A (ETA) and cholix toxin from Vibrio cholerae share the same mechanism of… 
Highly Cited
2008
Highly Cited
2008
Diphthamide modification of eEF2 requires a J-domain protein and is essential for normal development
The intracellular target of diphtheria toxin is a modified histidine residue, diphthamide, in the translation elongation factor… 
Highly Cited
2003
Highly Cited
2003
Elongator's toxin‐target (TOT) function is nuclear localization sequence dependent and suppressed by post‐translational modification
The toxin target (TOT) function of the Saccharomyces cerevisiae Elongator complex enables Kluyveromyces lactis zymocin to induce… 
1998
1998
Cloning and localization of a human diphthamide biosynthesis-like protein-2 gene, DPH2L2.
Sequence analysis of the candidate tumor suppressor OVCA1 revealed extensive sequence identity and similarity to proteins from a… 
1996
1996
A cDNA from the ovarian cancer critical region of deletion on chromosome 17p13.3.
1993
1993
Diphthamide synthesis in Saccharomyces cerevisiae: structure of the DPH2 gene.
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