Skip to search formSkip to main contentSkip to account menu

DOK1 protein, human

Known as: Docking Protein 1, Docking Protein 1, 62kD (Downstream of Tyrosine Kinase 1), Docking Protein, 62-kD 
Docking Protein 1, encoded by the human DOK1 gene, interacts with receptor tyrosine kinases and mediates particular biological responses. This 62-kD… 
National Institutes of Health

Related topics

Related topics

15 relations

Broader (3)

DNA-Binding ProteinsPhosphoproteinsRNA-Binding Proteins
DOK1 geneDocking -molecular interactionHeartHomo sapiens

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2007
2007
Differential regulation of adapter proteins Dok2 and Dok1 in platelets, leading to an association of Dok2 with integrin alphaIIbbeta3.
BACKGROUND We previously demonstrated that Dok2 is rapidly phosphorylated on tyrosine residues in platelets in response to… 
2006
2006
All‐trans retinoic acid induces p62DOK1 and p56DOK2 expression which enhances induced differentiation and G0 arrest of HL‐60 leukemia cells
p62DOK1 (DOK1) and p56DOK2 (DOK2) are sequence homologs that act as docking proteins downstream of receptor or nonreceptor… 
2004
2004
IkappaB kinase beta phosphorylates Dok1 serines in response to TNF, IL-1, or gamma radiation.
Dok1 is an abundant Ras-GTPase-activating protein-associated tyrosine kinase substrate that negatively regulates cell growth and… 
2002
2002
Signals mediated by FcγRIIA suppress the growth of B-lineage acute lymphoblastic leukemia cells
We examined Fc receptor expression and function in normal and leukemic human immature B cells. Fc receptor expression increased… 
2001
2001
T Cell Regulation of p62 dok (Dok1) Association with Crk-L*
In addition to engagement of the T cell receptor-CD3 complex, T lymphocytes can be activated by a variety of cell surface… 
2000
2000
Small nucleolar RNP scleroderma autoantigens associate with phosphorylated serine/arginine splicing factors during apoptosis.
OBJECTIVE Proteins that are phosphorylated during apoptosis are commonly precipitated by autoantibodies found in the sera of… 
1994
1994
A 62-kilodalton tyrosine phosphoprotein constitutively present in primary chronic phase chronic myelogenous leukemia enriched lineage negative blast populations.
Ph+ chronic myelogenous leukemia (CML) is associated with the reciprocal translocation between chromosomes 9 and 22 culminating… 
Review
1990
Review
1990
Substrates for Insulin-Receptor Kinase
Several studies suggest that the tyrosine-specific protein kinase activity of the β-subunit of the insulin receptor is necessary… 
1987
1987
Epidermal and transforming growth factors modulate secretion of a 69 kDa phosphoprotein in normal rat kidney fibroblasts
1985
1985
Altered processing of a major secreted phosphoprotein correlates with tumorigenicity in Rous sarcoma virus-transformed mammalian cells
Anchorage-independent growth is highly correlated with neoplastic growth in vivo, and the retinoids (vitamin A and its analogs… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)