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DOCK4 gene

Known as: DOCK4, KIAA0716, FLJ34238 
 
National Institutes of Health

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DOCK5 gene

Papers overview

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Highly Cited
2019
Highly Cited
2019
SR-B1 Drives Endothelial Cell LDL Transcytosis via DOCK4 to Promote Atherosclerosis
Atherosclerosis, which underlies life-threatening cardiovascular disorders such as myocardial infarction and stroke1, is… Expand
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Highly Cited
2013
Highly Cited
2013
The Atypical Guanine Nucleotide Exchange Factor Dock4 Regulates Neurite Differentiation through Modulation of Rac1 GTPase and Actin Dynamics*
Background: Dock4, a guanine nucleotide exchange factor for Rac1, is associated with neuropsychiatric diseases. Results: Dock4… Expand
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Highly Cited
2010
Highly Cited
2010
High-density SNP association study and copy number variation analysis of the AUTS1 and AUTS5 loci implicate the IMMP2L–DOCK4 gene region in autism susceptibility
Autism spectrum disorders are a group of highly heritable neurodevelopmental disorders with a complex genetic etiology. The… Expand
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Highly Cited
2010
Highly Cited
2010
Characterization of a Family with Rare Deletions in CNTNAP5 and DOCK4 Suggests Novel Risk Loci for Autism and Dyslexia
Background Autism spectrum disorders (ASDs) are characterized by social, communication, and behavioral deficits and complex… Expand
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Highly Cited
2008
Highly Cited
2008
Molecular association between β-catenin degradation complex and Rac guanine exchange factor DOCK4 is essential for Wnt/β-catenin signaling
The canonical Wnt/β-catenin pathway is a highly conserved signaling cascade that is involved in development and stem cell renewal… Expand
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Highly Cited
2008
Highly Cited
2008
Dock4 regulates dendritic development in hippocampal neurons
Dendrite development is required for establishing proper neuronal connectivity. Rho‐family small GTPases have been reported to… Expand
Highly Cited
2006
Highly Cited
2006
Dock4 is regulated by RhoG and promotes Rac-dependent cell migration.
Cell migration is essential for normal development and many pathological processes including tumor metastasis. Rho family GTPases… Expand
2006
2006
An isoform of GTPase regulator DOCK4 localizes to the stereocilia in the inner ear and binds to harmonin (USH1C).
The driving forces for the regulation of cell morphology are the Rho family GTPases that coordinate the assembly of the actin… Expand
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Highly Cited
2003
Highly Cited
2003
DOCK4, a GTPase Activator, Is Disrupted during Tumorigenesis
We used representational difference analysis to identify homozygous genomic deletions selected during tumor progression in the… Expand
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Highly Cited
1999
Highly Cited
1999
Evaluation of PMF scoring in docking weak ligands to the FK506 binding protein.
A new knowledge-based scoring function (PMF-score), implemented into the DOCK4 program, was used to screen a database of 3247… Expand
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