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DOCK4 gene
Known as:
DOCK4
, KIAA0716
, FLJ34238
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National Institutes of Health
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Related topics
Related topics
1 relation
DOCK5 gene
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2019
Highly Cited
2019
SR-B1 Drives Endothelial Cell LDL Transcytosis via DOCK4 to Promote Atherosclerosis
Linzhang Huang
,
K. Chambliss
,
+12 authors
P. Shaul
Nature
2019
Corpus ID: 129945333
Atherosclerosis, which underlies life-threatening cardiovascular disorders such as myocardial infarction and stroke1, is…
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Highly Cited
2015
Highly Cited
2015
TGF-β/Smad signaling through DOCK4 facilitates lung adenocarcinoma metastasis
Jia-Ray Yu
,
Yilin Tai
,
+5 authors
L. Van Aelst
Genes & Development
2015
Corpus ID: 206229970
Yu et al. report that in lung adenocarcinoma (ADC) cells, TGF-β potently induces expression of DOCK4, but not other DOCK family…
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2013
2013
Rac GEF Dock4 interacts with cortactin to regulate dendritic spine formation
Shuhei Ueda
,
M. Negishi
,
H. Katoh
Molecular Biology of the Cell
2013
Corpus ID: 11106076
Rac GEF Dock4, recently reported as a candidate genetic risk factor for autism, dyslexia, and schizophrenia, is highly…
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Highly Cited
2013
Highly Cited
2013
The Atypical Guanine Nucleotide Exchange Factor Dock4 Regulates Neurite Differentiation through Modulation of Rac1 GTPase and Actin Dynamics*
Yangui Xiao
,
Yinghui Peng
,
+6 authors
Lei Shi
Journal of Biological Chemistry
2013
Corpus ID: 8916918
Background: Dock4, a guanine nucleotide exchange factor for Rac1, is associated with neuropsychiatric diseases. Results: Dock4…
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Highly Cited
2010
Highly Cited
2010
Characterization of a Family with Rare Deletions in CNTNAP5 and DOCK4 Suggests Novel Risk Loci for Autism and Dyslexia
A. Pagnamenta
,
E. Bacchelli
,
+24 authors
A. Monaco
Biological Psychiatry
2010
Corpus ID: 2947550
Highly Cited
2009
Highly Cited
2009
High-density SNP association study and copy number variation analysis of the AUTS1 and AUTS5 loci implicate the IMMP2L–DOCK4 gene region in autism susceptibility
E. Maestrini
,
A. Pagnamenta
,
+21 authors
A. Monaco
Molecular Psychiatry
2009
Corpus ID: 13937940
Autism spectrum disorders are a group of highly heritable neurodevelopmental disorders with a complex genetic etiology. The…
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Highly Cited
2008
Highly Cited
2008
Molecular association between β-catenin degradation complex and Rac guanine exchange factor DOCK4 is essential for Wnt/β-catenin signaling
G. Upadhyay
,
W. Goessling
,
T. North
,
R. Xavier
,
L. Zon
,
V. Yajnik
Oncogene
2008
Corpus ID: 9057592
The canonical Wnt/β-catenin pathway is a highly conserved signaling cascade that is involved in development and stem cell renewal…
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Highly Cited
2008
Highly Cited
2008
Dock4 regulates dendritic development in hippocampal neurons
Shuhei Ueda
,
S. Fujimoto
,
Kiyo Hiramoto
,
M. Negishi
,
H. Katoh
Journal of Neuroscience Research
2008
Corpus ID: 10811745
Dendrite development is required for establishing proper neuronal connectivity. Rho‐family small GTPases have been reported to…
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Highly Cited
2003
Highly Cited
2003
DOCK4, a GTPase Activator, Is Disrupted during Tumorigenesis
V. Yajnik
,
C. Paulding
,
+9 authors
D. Haber
Cell
2003
Corpus ID: 18352801
Highly Cited
1999
Highly Cited
1999
Evaluation of PMF scoring in docking weak ligands to the FK506 binding protein.
I. Muegge
,
Y. Martin
,
P. Hajduk
,
S. Fesik
Journal of Medicinal Chemistry
1999
Corpus ID: 2759363
A new knowledge-based scoring function (PMF-score), implemented into the DOCK4 program, was used to screen a database of 3247…
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