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DNAJC19 gene

Known as: Tim14, DnaJ heat shock protein family (Hsp40) member C19, DNAJC19 
 
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
DNAJC19, a mitochondrial cochaperone associated with cardiomyopathy, forms a complex with prohibitins to regulate cardiolipin remodeling.
Prohibitins form large protein and lipid scaffolds in the inner membrane of mitochondria that are required for mitochondrial… Expand
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Highly Cited
2008
Highly Cited
2008
Interaction of the J-protein heterodimer Pam18/Pam16 of the mitochondrial import motor with the translocon of the inner membrane.
Import of proteins across the inner mitochondrial membrane through the Tim23:Tim17 translocase requires the function of an… Expand
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Highly Cited
2006
Highly Cited
2006
Mutation of DNAJC19, a human homologue of yeast inner mitochondrial membrane co-chaperones, causes DCMA syndrome, a novel autosomal recessive Barth syndrome-like condition
Background: A novel autosomal recessive condition, dilated cardiomyopathy with ataxia (DCMA) syndrome, has been identified in the… Expand
Highly Cited
2006
Highly Cited
2006
Structure and function of Tim14 and Tim16, the J and J‐like components of the mitochondrial protein import motor
The import motor of the mitochondrial translocase of the inner membrane (TIM23) mediates the ATP‐dependent translocation of… Expand
Highly Cited
2005
Highly Cited
2005
Mitochondrial Presequence Translocase: Switching between TOM Tethering and Motor Recruitment Involves Tim21 and Tim17
The presequence translocase of the inner mitochondrial membrane (TIM23 complex) operates at a central junction of protein import… Expand
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Highly Cited
2005
Highly Cited
2005
Pam17 Is Required for Architecture and Translocation Activity of the Mitochondrial Protein Import Motor
ABSTRACT Import of mitochondrial matrix proteins involves the general translocase of the outer membrane and the presequence… Expand
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Highly Cited
2004
Highly Cited
2004
Pam16 has an essential role in the mitochondrial protein import motor
Mitochondrial preproteins destined for the matrix are translocated by two channel-forming transport machineries, the translocase… Expand
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Highly Cited
2004
Highly Cited
2004
The Presequence Translocase-associated Protein Import Motor of Mitochondria
Transport of preproteins into the mitochondrial matrix requires the presequence translocase of the inner membrane (TIM23 complex… Expand
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Highly Cited
2003
Highly Cited
2003
Tim14, a novel key component of the import motor of the TIM23 protein translocase of mitochondria
The TIM23 translocase mediates the ΔΨ‐ and ATP‐dependent import of proteins into mitochondria. We identified Tim14 as a novel… Expand
Highly Cited
2003
Highly Cited
2003
J protein cochaperone of the mitochondrial inner membrane required for protein import into the mitochondrial matrix
The major Hsp70 of the mitochondrial matrix (Ssc1 in yeast) is critically important for the translocation of proteins from the… Expand
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