DNA replication factor A complex location

Known as: DNA replication factor A complex, RPA, replication protein A 
A conserved heterotrimeric complex that binds nonspecifically to single-stranded DNA and is required for multiple processes in eukaryotic DNA… (More)
National Institutes of Health

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Highly Cited
2013
Highly Cited
2013
Luis Ignacio Toledo,1 Matthias Altmeyer,1 Maj-Britt Rask,1 Claudia Lukas,1 Dorthe Helena Larsen,1 Lou Klitgaard Povlsen,2 Simon… (More)
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Review
2008
Review
2008
DNA mismatch repair (MMR) is a highly conserved biological pathway that plays a key role in maintaining genomic stability. The… (More)
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Highly Cited
2007
Highly Cited
2007
The Mre11-Rad50-Nbs1 (MRN) complex is a primary sensor of DNA double-strand breaks (DSBs). Upon recruitment to DSBs, it plays a… (More)
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Highly Cited
2006
Highly Cited
2006
The heterotrimeric checkpoint clamp comprises the Saccharomyces cerevisiae Rad17, Mec3, and Ddc1 subunits (Rad17/3/1, the 9-1-1… (More)
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Highly Cited
2000
Highly Cited
2000
Individuals affected by the autosomal recessive disorder Werner's syndrome (WS) develop many of the symptoms characteristic of… (More)
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Highly Cited
1998
Highly Cited
1998
Saccharomyces cells suffering a single unrepairable double-strand break (DSB) exhibit a long, but transient arrest at G2/M. hdf1… (More)
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Review
1997
Review
1997
Replication protein A [RPA; also known as replication factor A (RFA) and human single-stranded DNA-binding protein] is a single… (More)
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Review
1997
Review
1997
A wide range of cytotoxic and mutagenic DNA bases are removed by different DNA glycosylases, which initiate the base excision… (More)
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Highly Cited
1995
Highly Cited
1995
Nucleotide excision repair is the principal way by which human cells remove UV damage from DNA. Human cell extracts were… (More)
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Highly Cited
1993
Highly Cited
1993
THE tumour suppressor p53 specifically interferes with the onset of S phase. The mechanism of the growth suppression action of… (More)
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