DNA ligase III-XRCC1 complex
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Chemotherapy based on platinum compounds is the standard treatment for NSCLC patients with EGFR wild type, and is also used as… Expand Lung cancer is a multifactorial disease. Xeroderma pigmentosum group D (XPD) and X‐ray repair cross‐complementing 1 (XRCC1) genes… Expand XRCC1 is a scaffold protein that provides for interaction of DNA polymerase, DNA ligase and damaged DNA. Genotyping was done for… Expand Genetic variants found in DNA repair genes (ERCC1, rs3212986; ERCC2, rs13181; ERCC4, rs1800067; ERCC5, rs17655; XRCC1, rs1799782… Expand BACKGROUND
Stomach cancer is one of leading causes of death worldwide. In Thailand, the incidence and mortality of stomach cancer… Expand Individual differences in chemosensitivity and clinical outcome of non-small-cell lung carcinoma (NSCLC) patients can be… Expand Polymorphisms in DNA repair genes have been shown to influence DNA repair processes and to modify cancer susceptibility. Here we… Expand XRCC1 genetic polymorphisms could be associated with increased risk of various cancer, including hepatocellular carcinoma (HCC… Expand AIM
XRCC1 and XPD are two major repair genes involved in nucleotide excision repair (NER), which is reported to be associated… Expand Frequencies of spontaneous and γ-induced (1 Gy in vitro) chromosome aberrations in blood lymphocytes of 99 healthy volunteers… Expand