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DNA ligase III-XRCC1 complex

Known as: DNA ligase III-XRCC1 complex location 
A protein complex that contains DNA ligase III and XRCC1, and is involved in base excision repair. [PMID:15141024, PMID:7760816]
National Institutes of Health

Papers overview

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2018
2018
Pharmacogenetics of platinum-based chemotherapy: impact of DNA repair and folate metabolism gene polymorphisms on prognosis of non-small cell lung cancer patients
Chemotherapy based on platinum compounds is the standard treatment for NSCLC patients with EGFR wild type, and is also used as… Expand
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2016
2016
Association between genetic polymorphisms in XPD and XRCC1 genes and risks of non-small cell lung cancer in East Chinese Han population.
BACKGROUND AND AIMS Lung cancer is a multifactorial disease. Xeroderma pigmentosum group D (XPD) and X-ray repair cross… Expand
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2016
2016
A Comprehensive Meta-analysis of Genetic Associations Between Key Polymorphic Loci in DNA Repair Genes and Glioma Risk
Genetic variants found in DNA repair genes (ERCC1, rs3212986; ERCC2, rs13181; ERCC4, rs1800067; ERCC5, rs17655; XRCC1, rs1799782… Expand
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2016
2016
Association and multiple interaction analysis among five XRCC1 polymorphic variants in modulating lung cancer risk in North Indian population.
XRCC1 is a scaffold protein that provides for interaction of DNA polymerase, DNA ligase and damaged DNA. Genotyping was done for… Expand
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2015
2015
XRCC1 Gene Polymorphism, Clinicopathological Characteristics and Stomach Cancer Survival in Thailand.
BACKGROUND Stomach cancer is one of leading causes of death worldwide. In Thailand, the incidence and mortality of stomach cancer… Expand
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2014
2014
Pharmacogenetics of DNA repair gene polymorphisms in non-small-cell lung carcinoma patients on platinum-based chemotherapy.
Individual differences in chemosensitivity and clinical outcome of non-small-cell lung carcinoma (NSCLC) patients can be… Expand
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2013
2013
Polymorphisms in DNA repair genes and risk of glioma and meningioma.
Polymorphisms in DNA repair genes have been shown to influence DNA repair processes and to modify cancer susceptibility. Here we… Expand
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2013
2013
Implication of polymorphisms in DNA repair genes in prognosis of hepatocellular carcinoma.
XRCC1 genetic polymorphisms could be associated with increased risk of various cancer, including hepatocellular carcinoma (HCC… Expand
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2012
2012
Association of XPD and XRCC1 genetic polymorphisms with hepatocellular carcinoma risk.
AIM XRCC1 and XPD are two major repair genes involved in nucleotide excision repair (NER), which is reported to be associated… Expand
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2010
2010
Polymorphism of repair genes and cytogenetic radiation effects
Frequencies of spontaneous and γ-induced (1 Gy in vitro) chromosome aberrations in blood lymphocytes of 99 healthy volunteers… Expand
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