DNA excision

The removal of a section of DNA from a larger DNA molecule by the making of dual incisions that flank the section to be excised. [GOC:jl]

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Topic mentions per year

1973-2017
0102019732017

Papers overview

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2010
2010
Transposons comprise large fractions of eukaryotic genomes and provide genetic reservoirs for the evolution of new cellular… (More)
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Highly Cited
2007
Highly Cited
2007
HIV-1 integrates into the host chromosome and persists as a provirus flanked by long terminal repeats (LTRs). To date, treatment… (More)
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Highly Cited
2001
Highly Cited
2001
We have developed a chemical-inducible, site-specific DNA excision system in transgenic Arabidopsis plants mediated by the Cre… (More)
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Highly Cited
1999
Highly Cited
1999
Conditional DNA excision between two LoxP sites can be achieved in the mouse using Cre-ER(T), a fusion protein between a mutated… (More)
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Highly Cited
1998
Highly Cited
1998
BACKGROUND/AIMS Diminished folate status appears to promote colonic carcinogenesis by, as of yet, undefined mechanisms. Impaired… (More)
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1997
Highly Cited
1997
The site-specific DNA recombinase Cre is being used to develop a new generation of tools for controlling gene expression in mice… (More)
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Highly Cited
1995
Highly Cited
1995
Xeroderma pigmentosum patients with a defect in the nucleotide-excision repair gene XPA are characterized by, for example, a > 1… (More)
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1994
Highly Cited
1994
GADD45 is a ubiquitously expressed mammalian gene that is induced by DNA damage and certain other stresses. Like another p53… (More)
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Highly Cited
1992
Highly Cited
1992
Fractionation of extracts from human cell lines allows nucleotide excision repair of damaged DNA to be resolved into discrete… (More)
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Highly Cited
1990
Highly Cited
1990
Cell death induced by cisplatin was studied in Chinese hamster ovary cell lines, one proficient and the other deficient (100-fold… (More)
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