DNA cytosine deamination

The removal of an amino group from a cytosine residue in DNA, forming a uracil residue. [GOC:mah]
National Institutes of Health

Topic mentions per year

Topic mentions per year

2006-2017
01220062017

Papers overview

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2017
2017
APOBEC-catalyzed cytosine-to-uracil deamination of single-stranded DNA (ssDNA) has beneficial functions in immunity and… (More)
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2017
2017
The APOBEC3 DNA cytosine deaminase family comprises a fundamental arm of the innate immune response and is best known for… (More)
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Review
2015
Review
2015
UNLABELLED Deep sequencing technologies are revealing the complexities of cancer evolution, casting light on mutational processes… (More)
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2013
2013
Knowledge of cancer genomic DNA sequences has created unprecedented opportunities for mutation studies. Computational analyses… (More)
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2013
2013
Activation-induced cytidine deaminase (AID) is a DNA mutator enzyme essential for adaptive immunity. AID initiates somatic… (More)
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Review
2013
Review
2013
The ability to regulate and even target mutagenesis is an extremely valuable cellular asset. Enzyme-catalyzed DNA cytosine… (More)
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2012
2012
Members of the APOBEC (apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like) protein family catalyze DNA cytosine… (More)
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2010
2010
The mutagenic threat of hydrolytic DNA cytosine deamination is met mostly by uracil DNA glycosylases (UDG) initiating base… (More)
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Highly Cited
2008
Highly Cited
2008
Human APOBEC3G and several other APOBEC3 proteins have been shown to inhibit the replication of a variety of retrotransposons and… (More)
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2006
2006
The APOBEC3 proteins are unique to mammals. Many inhibit retrovirus infection through a cDNA cytosine deamination mechanism. HIV… (More)
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