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DNA Polymerase II

Known as: DNA Pol II, DNA Dependent DNA Polymerase II, DNA Polymerase II [Chemical/Ingredient] 
A DNA-dependent DNA polymerase characterized in E. coli and other lower organisms. It may be present in higher organisms and has an intrinsic… Expand
National Institutes of Health

Related topics

Related topics

14 relations
DNA Polymerase IDNA polymerase II activityIn BloodPOLE gene
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Broader (1)

DNA-Directed DNA Polymerase

Narrower (2)

DPB3-1 protein, ArabidopsisPOLE protein, human

Papers overview

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Highly Cited
2014
Highly Cited
2014
Exonuclease mutations in DNA polymerase epsilon reveal replication strand specific mutation patterns and human origins of replication.
Tumors with somatic mutations in the proofreading exonuclease domain of DNA polymerase epsilon (POLE-exo*) exhibit a novel… Expand
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Highly Cited
2008
Highly Cited
2008
Mrc1 and DNA polymerase epsilon function together in linking DNA replication and the S phase checkpoint.
Yeast Mrc1, ortholog of metazoan Claspin, is both a central component of normal DNA replication forks and a mediator of the S… Expand
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Highly Cited
2007
Highly Cited
2007
Yeast DNA polymerase epsilon participates in leading-strand DNA replication.
Multiple DNA polymerases participate in replicating the leading and lagging strands of the eukaryotic nuclear genome. Although 50… Expand
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Highly Cited
1999
Highly Cited
1999
DNA polymerase II (polB) is involved in a new DNA repair pathway for DNA interstrand cross-links in Escherichia coli.
DNA-DNA interstrand cross-links are the cytotoxic lesions for many chemotherapeutic agents. A plasmid with a single nitrogen… Expand
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Highly Cited
1996
Highly Cited
1996
Mechanism of Translesion DNA Synthesis by DNA Polymerase II
Bypass synthesis by DNA polymerase II was studied using a synthetic 40-nucleotide-long gapped duplex DNA containing a site… Expand
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Highly Cited
1992
Highly Cited
1992
DNA polymerase II, the probable homolog of mammalian DNA polymerase epsilon, replicates chromosomal DNA in the yeast Saccharomyces cerevisiae.
Two temperature‐sensitive DNA polymerase II mutants (pol2‐9 and pol2‐18) of the yeast Saccharomyces cerevisiae were isolated by… Expand
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Highly Cited
1992
Highly Cited
1992
Processive DNA synthesis by DNA polymerase II mediated by DNA polymerase III accessory proteins.
An interesting property of the Escherichia coli DNA polymerase II is the stimulation in DNA synthesis mediated by the DNA… Expand
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Highly Cited
1991
Highly Cited
1991
Cloning DPB3, the gene encoding the third subunit of DNA polymerase II of Saccharomyces cerevisiae.
DNA polymerase II purified from Saccharomyces cerevisiae contains polypeptides with apparent molecular masses of greater than 200… Expand
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Highly Cited
1991
Highly Cited
1991
DPB2, the gene encoding DNA polymerase II subunit B, is required for chromosome replication in Saccharomyces cerevisiae.
The Saccharomyces cerevisiae DNA polymerase II holoenzyme consists of five polypeptides. The largest is the catalytic subunit… Expand
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Highly Cited
1990
Highly Cited
1990
DNA polymerase II is encoded by the DNA damage-inducible dinA gene of Escherichia coli.
The structural gene for DNA polymerase II was cloned by using a synthetic inosine-containing oligonucleotide probe corresponding… Expand
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