DNA Polymerase II

Known as: DNA Pol II, DNA Dependent DNA Polymerase II, DNA Polymerase II [Chemical/Ingredient] 
A DNA-dependent DNA polymerase characterized in E. coli and other lower organisms. It may be present in higher organisms and has an intrinsic… (More)
National Institutes of Health

Related topics

Related topics

14 relations
DNA Polymerase IDNA polymerase II activityIn BloodPOLE gene
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Broader (1)

DNA-Directed DNA Polymerase

Narrower (2)

DPB3-1 protein, ArabidopsisPOLE protein, human

Papers overview

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Highly Cited
2014
Highly Cited
2014
Exonuclease mutations in DNA polymerase epsilon reveal replication strand specific mutation patterns and human origins of replication.
Tumors with somatic mutations in the proofreading exonuclease domain of DNA polymerase epsilon (POLE-exo*) exhibit a novel… (More)
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Highly Cited
2009
Highly Cited
2009
Translesion DNA polymerases remodel the replisome and alter the speed of the replicative helicase.
All cells contain specialized translesion DNA polymerases that replicate past sites of DNA damage. We find that Escherichia coli… (More)
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Highly Cited
2008
Highly Cited
2008
Mrc1 and DNA polymerase epsilon function together in linking DNA replication and the S phase checkpoint.
Yeast Mrc1, ortholog of metazoan Claspin, is both a central component of normal DNA replication forks and a mediator of the S… (More)
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Highly Cited
2007
Highly Cited
2007
Yeast DNA polymerase epsilon participates in leading-strand DNA replication.
Multiple DNA polymerases participate in replicating the leading and lagging strands of the eukaryotic nuclear genome. Although 50… (More)
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2000
2000
Identification and cloning of two histone fold motif-containing subunits of HeLa DNA polymerase epsilon.
HeLa DNA polymerase epsilon (pol epsilon), possibly involved in both DNA replication and DNA repair, was previously isolated as a… (More)
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1999
1999
DNA polymerase II (polB) is involved in a new DNA repair pathway for DNA interstrand cross-links in Escherichia coli.
DNA-DNA interstrand cross-links are the cytotoxic lesions for many chemotherapeutic agents. A plasmid with a single nitrogen… (More)
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1991
1991
Cloning DPB3, the gene encoding the third subunit of DNA polymerase II of Saccharomyces cerevisiae.
DNA polymerase II purified from Saccharomyces cerevisiae contains polypeptides with apparent molecular masses of greater than 200… (More)
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1991
1991
DPB2, the gene encoding DNA polymerase II subunit B, is required for chromosome replication in Saccharomyces cerevisiae.
The Saccharomyces cerevisiae DNA polymerase II holoenzyme consists of five polypeptides. The largest is the catalytic subunit… (More)
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1990
1990
The Escherichia coli polB gene, which encodes DNA polymerase II, is regulated by the SOS system.
The dinA (damage inducible) gene was previously identified as one of the SOS genes with no known function; it was mapped near the… (More)
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1990
1990
DNA polymerase II is encoded by the DNA damage-inducible dinA gene of Escherichia coli.
The structural gene for DNA polymerase II was cloned by using a synthetic inosine-containing oligonucleotide probe corresponding… (More)
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