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Background Human melanoma is a malignant tumor that originates from abnormal growth of melanocytes. It is the most lethal form of… Expand DMU-212 has been shown to evoke a mitochondrial apoptotic pathway in transformed fibroblasts and breast cancer. However, recently… Expand It has been reported that methylated analog of resveratrol, 3,4,5,4′-trans-tetramethoxystilbene (DMU-212), demonstrates strong… Expand The cytotoxic activity of DMU-212 has been shown to vary in cell lines derived from the same type of cancer, i.e. ovarian, breast… Expand In the screening studies, cytotoxicity of 12 methylated resveratrol analogues on 11 human cancer cell lines was examined. The… Expand A variety of triethylallyl and triethylbenzyl phosphonium bromides is prepared with nearly quantitative yields by the direct… Expand The Wittig reaction involving direct olefination of triphenylphosphonium ylides (Ph(3)P horizontal lineCHR) with aldehydes is… Expand PurposeResveratrol is a well-known chemopreventive and chemotherapeutic agent. Among all of the resveratrol analogs synthesized… Expand A concise route to combretastatin A-4, a potent inhibitor of tubulin polymerisation, using a Ramberg-Bäcklund reaction to form… Expand Naturally occurring molecules with putative cancer chemopreventive properties such as the phytoalexin resveratrol (3,5,4… Expand