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DMP1 gene

Known as: DENTIN MATRIX ACIDIC PHOSPHOPROTEIN 1, DMP1, Dentin Matrix Acidic Phosphoprotein 1 Gene 
This gene plays a role in osteoblast differentiation and ossification.
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Osteocytes represent the most abundant cellular component of mammalian bones with important functions in bone mass maintenance… Expand
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Highly Cited
2008
Highly Cited
2008
Autosomal recessive hypophosphatemic rickets (ARHR), which is characterized by renal phosphate wasting, aberrant regulation of… Expand
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Highly Cited
2007
Highly Cited
2007
Dentin matrix protein 1 (DMP1) is expressed in both pulp and odontoblast cells and deletion of the Dmp1 gene leads to defects in… Expand
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Highly Cited
2006
Highly Cited
2006
The osteocyte, a terminally differentiated cell comprising 90%–95% of all bone cells, may have multiple functions, including… Expand
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Highly Cited
2006
Highly Cited
2006
Hypophosphatemia is a genetically heterogeneous disease. Here, we mapped an autosomal recessive form (designated ARHP) to… Expand
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Highly Cited
2005
Highly Cited
2005
The role of DMP1 in mineralization was analyzed by comparing bone mineral and matrix properties in dmp1‐null female mice to… Expand
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Highly Cited
2005
Highly Cited
2005
ABSTRACT Dmp1 prevents tumor formation by activating the Arf-p53 pathway. In cultured primary cells, the Dmp1 promoter was… Expand
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Highly Cited
2005
Highly Cited
2005
Understanding the molecular mechanisms by which cartilage formation is regulated is essential toward understanding the physiology… Expand
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Highly Cited
2004
Highly Cited
2004
Dentin matrix protein-1 (DMP1) is a mineralized tissue matrix protein synthesized by osteoblasts, hypertrophic chondrocytes, and… Expand
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Highly Cited
2003
Highly Cited
2003
Dentin Matrix Protein 1 (Dmp1) was originally identified from dentin. However, its expression and function in vivo are not clear… Expand
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