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DLEU2 Protein

Known as: DLEU2, Leukemia Associated Protein 2 
Expressed in thymus and testis and encoded by human DLEU2 Gene, DLEU2 Protein is an 84-amino acid 10-kD putative tumor suppressor protein. (from… 
National Institutes of Health

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Cell Proliferation Regulatory ProcessDLEU2 geneDLEU2 wt AlleleHomo sapiens
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Papers overview

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2020
2020
Hepatitis B protein HBx binds the DLEU2 lncRNA to sustain cccDNA and host cancer-related gene transcription
Objective The HBV HBx regulatory protein is required for transcription from the covalently closed circular DNA (cccDNA… 
2020
2020
Long noncoding RNA DLEU2 predicts a poor prognosis and enhances malignant properties in laryngeal squamous cell carcinoma through the miR-30c-5p/PIK3CD/Akt axis
Long noncoding RNAs (lncRNAs) have been identified as potential prognostic tools and therapeutic biomarkers for a variety of… 
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2019
2019
Silencing of DLEU2 suppresses pancreatic cancer cell proliferation and invasion by upregulating microRNA‐455
Long noncoding RNA (lncRNA) DLEU2 has been shown to be dysregulated in several type of tumor. However, the potential biological… 
2019
2019
lncRNA DLEU2 modulates cell proliferation and invasion of non-small cell lung cancer by regulating miR-30c-5p/SOX9 axis
Increasing evidence indicated that long noncoding RNAs (lncRNA) play critical roles in the progression of multiple cancers and… 
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2018
2018
Role of Circular RNA DLEU2 in Human Acute Myeloid Leukemia
In the current study, we were interested in exploring the molecular mechanism of circular RNA DLEU2 (circRNA-DLEU2… 
2018
2018
Integrative Analysis of Dysregulated lncRNA-Associated ceRNA Network Reveals Functional lncRNAs in Gastric Cancer
Mounting evidence suggests that long noncoding RNAs (lncRNAs) play important roles in the regulation of gene expression by acting… 
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2018
2018
Long non-coding RNA Dleu2 affects proliferation, migration and invasion ability of laryngeal carcinoma cells through triggering miR-16-1 pathway.
OBJECTIVE Laryngeal cancer is a common malignant tumor in the head and neck, which affects swallowing, breathing, and… 
Review
2013
Review
2013
Role of microRNA in the pathogenesis of malignant lymphoma
MicroRNA (miRNA) are non‐coding regulatory RNA usually consisting of 20−24 nucleotides. Over the past decade, increases and… 
Highly Cited
2009
Highly Cited
2009
DLEU2, frequently deleted in malignancy, functions as a critical host gene of the cell cycle inhibitory microRNAs miR-15a and miR-16-1.
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2004
2004
DLEU2 encodes an antisense RNA for the putative bicistronic RFP2/LEU5 gene in humans and mouse
Our group previously identified two novel genes, RFP2/LEU5 and DLEU2, within a 13q14.3 genomic region of loss seen in various… 
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