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Background The decline of a long non-coding RNA (lncRNA) DIO3OS was implicated in a plethora of cancers, while the relevance in… Expand BackgroundLong noncoding RNA (lncRNA) has been implicated in numerous tumors, including pancreatic cancer (PC). However, the… Expand Long non-coding RNAs (lncRNAs) are a novel group of non-coding RNAs that are associated with inflammation and tumorigenesis. At… Expand DIO3 and DIO3OS are two imprinted genes identified in mouse and humans. The DIO3 gene, which encodes for the type 3 deiodinase… Expand Thyroid dysfunction during human pregnancy is closely related to serious pregnancy outcome. However, the regulation and function… Expand Genomic imprinting, the preferential expression of maternal or paternal alleles of imprinted genes, is often maintained through… Expand The functioning of the genome is tightly related to its architecture. Therefore, understanding the relationship between different… Expand Active thyroid hormones are critical for the differentiation and function of brown adipose tissue. However, we have observed high… Expand Type I iodothyronine deiodinase (D1) and type II iodothyronine deiodinase (D2) catalyze the activation of the prohormone T4 to… Expand The human DIO3 gene and its mouse homolog, Dio3, map to chromosomes 14q32 and 12F1, respectively, and code for the type 3… Expand