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Activation of p53 by the small molecule Nutlin can result in a combination of cell cycle arrest and apoptosis. The relative… Expand Intellectual disability (ID) affects at least 1% of the population, and typically presents in the first few years of life. ID is… Expand Abstract Influenza A viruses cause widespread human respiratory disease. The viral multifunctional NS1 protein inhibits host… Expand Introduction The transcription factor p53 can be efficiently activated by the small molecule Nutlin-3 without inducing genotoxic… Expand DHX30 is a member of the family of DExH-box helicases, which use ATP hydrolysis to unwind RNA secondary structures. Here we… Expand BackgroundGiven the rarity of most single-gene Mendelian disorders, concerted efforts of data exchange between clinical and… Expand The gene trap method for embryonic stem cells is an efficient method for identifying new genes that are involved in development… Expand The gene trap method for embryonic stem cells is an efficient method for identifying new genes that are involved in development… Expand The zinc-finger antiviral protein (ZAP) is a host factor that specifically inhibits the replication of certain viruses by… Expand