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DG172

National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Peroxisome Proliferator-activated Receptor-D (PPARD) Coordinates Mouse Spermatogenesis by Modulating Extracellular Signal-regulated Kinase (ERK)-dependent Signaling*
Background: The role of PPARD was examined in the testes because this receptor can regulate cell differentiation and… 
2015
2015
PPARD regulates ERK signaling in the testis
Ppard mice exhibit smaller litter size compared to Ppard mice. To determine whether peroxisome proliferator-activated receptor-D… 
2012
2012
(Z)-2-(2-bromophenyl)-3-{[4-(1-methyl-piperazine)amino]phenyl}acrylonitrile (DG172): an orally bioavailable PPARβ/δ-selective ligand with inverse agonistic properties.
The ligand-regulated nuclear receptor peroxisome proliferator-activated receptor β/δ (PPARβ/δ) is a potential pharmacological… 
Highly Cited
2012
Highly Cited
2012
Inverse PPARβ/δ agonists suppress oncogenic signaling to the ANGPTL4 gene and inhibit cancer cell invasion
Besides its established functions in intermediary metabolism and developmental processes, the nuclear receptor peroxisome… 
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