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DG 5128

Known as: DG-5128 
National Institutes of Health

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midaglizole

Papers overview

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1991
1991
Mechanisms involved in stimulation of insulin secretion by the hypoglycaemic alpha-adrenergic antagonist, DG-5128.
1989
1989
The inhibitory effect of a selective alpha 2-adrenergic receptor antagonist on moderate- to severe-type asthma.
1989
1989
Pharmacologic characterization of the receptor mediating the hypnotic action of dexmedetomidine.
The anesthetic-reducing property of medetomidine far exceeds that seen with other alpha 2-adrenergic agonists (e.g., clonidine… 
1988
1988
Inhibitory effect of DG-5128 on steroid-dependent asthma.
To study the possible role of alpha-2 receptors in intractable asthmatics, we investigated the ameliorative effects of 2-[2-(4,5… 
1987
1987
Initial Phase II Clinical Studies on Midaglizole (DG-5128): A New Hypoglycemic Agent
Midaglizole (DG-5128), 2-[2-(4,5-dihydro-1H-imidazol-2-yl)-1-phenylethyl]pyridine dihydrochloride sesquihydrate, is a new type of… 
Highly Cited
1987
Highly Cited
1987
Studies of Midaglizole (DG-5128): A New Type of Oral Hypoglycemic Drug in Healthy Subjects
Midaglizole (DG-5128), 2-[2-(4,5-dihydro-1H-imidazol-2- yl)-1-phenylethyl]pyridine dihydrochloride sesquihydrate, is a novel α2… 
Highly Cited
1986
Highly Cited
1986
New α2-Adrenergic Blocker (DG-5128) Improves Insulin Secretion and In Vivo Glucose Disposal in NIDDM Patients
Effects of oral administration of DG-5128, a new oral hypoglycemic agent, on glycemic control after a mixed meal and an in vivo… 
1985
1985
Selective interaction of DG-5128 with a low agonist affinity state of alpha-2 adrenoceptor.
Using rat cerebral cortex membranes, the inhibitory effect of DG-5128 against (3H)-clonidine binding was compared between low… 
1982
1982
Insulin releasing action of 2-[2-(4,5-dihydro-1H-imadazol-2-yl)-1-phenylethyl] pyridine dihydrochloride sesquihydrate (DG-5128), a new, orally effective hypoglycaemic agent.
2-[2-(4,5-dihydro-1H-imidazol-2-yl)-1-phenylethyl] pyridine dihydrochloride sesquilhydrate (DG-5128) is a new orally effective… 
1982
1982
Hypoglycemic action of 2-[2-(4,5-dihydro-1H-imidazol-2-yl)-1-phenylethyl]pyridine dihydrochloride sesquihydrate (DG-5128), a new hypoglycemic agent.
2-[2-(4,5-Dihydro-1H-imidazol-2-yl)-1-phenylethyl]pyridine dihydrochloride sesquihydrate (GD-5128) is a new hypoglycemic agent… 
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