DEVDase
National Institutes of Health
Papers overview
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The role of caspases and calpains in neurodegeneration remains unclear. In this study, we focused on these proteases in a rat…
To investigate the mechanisms underlying apoptosis in breast cancer cells, staurosporine was used as an apoptotic stimulus in the…
These studies have addressed the role of caspase-3 activation in neuronal death after cerebral ischemia in different animal…
To detect caspase activities in intact apoptotic cells at the single cell level, cell-permeable fluorogenic caspase substrates…
Photodamage to the mitochondria of murine leukemia P388 cells resulted in immediate loss of the mitochondrial membrane potential…
Although nitric oxide (NO) induces neuronal cell death under some conditions, it also can prevent apoptosis resulting from growth…
Using an episomal eucaryotic expression vector, we derived three stable transfected human leukemic U-937 variant lines showing…
Mitochondrial alterations including permeability transition (PT) constitute critical events of the apoptotic cascade and are…