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DEVDase

National Institutes of Health

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Peptide Hydrolases

Papers overview

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2005
2005
Involvement of NF-kappaB and mitochondrial pathways in docetaxel-induced apoptosis of human oral squamous cell carcinoma.
Apoptosis induced by docetaxel that interferes with microtubule polymerization dynamics and is used clinically to treat advanced… 
2005
2005
Enteroviral modulation of host cell and drug-induced apoptosis.
Coxsackievirus B4 (CVB4) is a common infection. Most cases are symptom-free but occasionally chronic sequelae emerge such as… 
2003
2003
B cell receptor‐mediated nuclear fragmentation proceeds in WEHI 231 cells in the absence of detectable DEVDase and FRase activity
2002
2002
Expression, proteolysis and activation of caspases 6 and 7 during rat C6 glioma cell apoptosis
2001
2001
Apoptotic morphology does not always require caspase activity in rat cerebellar granule neurons
The death of a cell via apoptosis is characterized by morphological changes including cell shrinkage and nuclear condensation… 
2001
2001
Mécanismes physiopathologiques et méthodes d’analyse de l’apoptose cellulaire
2001
2001
CD95-Related Apoptotic Machinery Is Functional in Pancreatic Cancer Cells
The CD95 (FAS, Apo-1) system is a major death pathway in normal and tumor cells. Recent evidence indicates that pancreatic cancer… 
2001
2001
In vivo and in vitro evidence for extracellular caspase activity released from apoptotic cells.
While caspases play an established role as intracellular executors of apoptosis, little is known about extracellular activities… 
2001
2001
Selective degradation of the PKC-epsilon isoform during cell death in AKR-2B fibroblasts.
The protein kinase C (PKC) family of serine/threonine protein kinases is involved in intracellular signals that regulate growth… 
1998
1998
Bcl-xL modulates apoptosis induced by anticancer drugs and delays DEVDase and DNA fragmentation-promoting activities.
Using an episomal eucaryotic expression vector, we derived three stable transfected human leukemic U-937 variant lines showing… 
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