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DCTN1 gene

Known as: p150 glued homolog (Drosophila), DYNACTIN 1, DCTN1 
This gene is involved in the modulation of retrograde transport of cytoplasmic organelles and vesicles.
National Institutes of Health

Related topics

Related topics

9 relations
DCTN3 geneDCTN6 geneDynactin Subunit 1, humanHomo sapiens

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Perry syndrome: a case of atypical parkinsonism with confirmed DCTN1 mutation.
Perry syndrome is a rare neurological condition characterised clinically by depression, sleep disturbance, central… 
2016
2016
Alteration of Motor Protein Expression Involved in Bidirectional Transport in Peripheral Blood Mononuclear Cells of Patients with Amyotrophic Lateral Sclerosis
Background: Sporadic amyotrophic lateral sclerosis (SALS) is a fatal motor neuron degenerative disease of unclear pathogenesis… 
2016
2016
Mutation analysis of genes within the dynactin complex in a cohort of hereditary peripheral neuropathies
The cytoplasmic dynein–dynactin genes are attractive candidates for neurodegenerative disorders given their functional role in… 
2015
2015
LRRK1-phosphorylated CLIP-170 regulates EGFR trafficking by recruiting p150Glued to microtubule plus ends
ABSTRACT The binding of ligand to epidermal growth factor receptor (EGFR) causes the receptor to become activated and stimulates… 
2008
2008
DCTN1 mutations in families with parkinsonism, depression, weight loss and central hypoventilation: Perry syndrome
2008
2008
VAPB
Although cases of amyotrophic lateral sclerosis (ALS) were described in the early and mid-19th century, in 1874, Jean-Martin… 
Review
2007
Review
2007
[Gene expression profile of spinal ventral horn in ALS].
The causative pathomechanism of sporadic amyotrophic lateral sclerosis (ALS) is not clearly understood. Using microarray… 
1998
1998
Human DCTN1: genomic structure and evaluation as a candidate for Alström syndrome.
The human dynactin 1 gene (DCTN1) is positioned on chromosome 2p13, the candidate region for various diseases including Alström… 
1997
1997
Integrated radiation hybrid map of human chromosome 2p13: possible involvement of dynactin in neuromuscular diseases.
The genes for the human neuromuscular diseases limb-girdle muscular dystrophy type 2B (LGMD2B) and Miyoshi myopathy are located… 
1997
1997
Mouse p150Glued (dynactin 1) cDNA sequence and evaluation as a candidate for the neuromuscular disease mutation mnd2.
p150Glued (Dynactin 1) is a component of the dynactin complex that is essential for retrograde axonal transport in neurons. The… 
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