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DAS181

Known as: 273-666-Neuraminidase [273-Methionine] (Actinomyces viscosus Clone DAS181) Fusion Protein With 125-145-Preproamphiregulin (Human), DAS181-F02, Recombinant Cell-Surface Anchored Sialidase DAS181 
A recombinant sialidase fusion protein composed of a sialidase catalytic domain derived from Actinomyces viscosus, a constituent of the normal oral… Expand
National Institutes of Health

Papers overview

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2016
2016
Parainfluenza virus (PIV) causes severe respiratory infections in hematopoietic stem cell transplant (HSCT) recipients. Currently… Expand
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Highly Cited
2012
Highly Cited
2012
BACKGROUND DAS181, a novel host-directed antiviral in development for influenza treatment, was assessed in this phase II clinical… Expand
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Review
2012
Review
2012
The emergence and global spread of the 2009 pandemic H1N1 influenza virus reminds us that we are limited in the strategies… Expand
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Highly Cited
2011
Highly Cited
2011
Parainfluenza virus (PIV) can cause significant morbidity after allogeneic stem cell transplantation (SCT). We report the first… Expand
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Review
2010
Review
2010
The emergence of the 2009 H1N1 pandemic influenza A virus, as well as constant antigenic drift of seasonal influenza, underscores… Expand
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Highly Cited
2009
Highly Cited
2009
Background The recent emergence of a novel pandemic influenza A(H1N1) strain in humans exemplifies the rapid and unpredictable… Expand
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Highly Cited
2009
Highly Cited
2009
Antiviral drug resistance for influenza therapies remains a concern due to the high prevalence of H1N1 2009 seasonal influenza… Expand
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Highly Cited
2009
Highly Cited
2009
ABSTRACT DAS181 is a novel candidate therapeutic agent against influenza virus which functions via the mechanism of removing the… Expand
Highly Cited
2007
Highly Cited
2007
Increasing resistance to currently available influenza antivirals highlights the need to develop alternate approaches for the… Expand
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Highly Cited
2006
Highly Cited
2006
ABSTRACT Influenza is a highly infectious disease characterized by recurrent annual epidemics and unpredictable major worldwide… Expand