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DAS181

Known as: 273-666-Neuraminidase [273-Methionine] (Actinomyces viscosus Clone DAS181) Fusion Protein With 125-145-Preproamphiregulin (Human), DAS181-F02, Recombinant Cell-Surface Anchored Sialidase DAS181 
A recombinant sialidase fusion protein composed of a sialidase catalytic domain derived from Actinomyces viscosus, a constituent of the normal oral… Expand
National Institutes of Health

Papers overview

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2016
2016
Parainfluenza virus (PIV) causes severe respiratory infections in hematopoietic stem cell transplant (HSCT) recipients. Currently… Expand
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2014
2014
Human infections caused by avian influenza A virus type subtype H7N9 have been associated with substantial morbidity and… Expand
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Highly Cited
2012
Highly Cited
2012
BACKGROUND DAS181, a novel host-directed antiviral in development for influenza treatment, was assessed in this phase II clinical… Expand
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2012
2012
Parainfluenza virus (PIV) infections can cause serious respiratory infections and death in immunocompromised patients. No… Expand
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Highly Cited
2009
Highly Cited
2009
Background The recent emergence of a novel pandemic influenza A(H1N1) strain in humans exemplifies the rapid and unpredictable… Expand
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Highly Cited
2009
Highly Cited
2009
ABSTRACT DAS181 is a novel candidate therapeutic agent against influenza virus which functions via the mechanism of removing the… Expand
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Highly Cited
2009
Highly Cited
2009
Antiviral drug resistance for influenza therapies remains a concern due to the high prevalence of H1N1 2009 seasonal influenza… Expand
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Review
2009
Review
2009
  • F. Hayden
  • Clinical infectious diseases : an official…
  • 2009
  • Corpus ID: 205988354
Antiviral agents for the treatment of influenza are urgently needed to circumvent the limitations of current drugs in several… Expand
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Highly Cited
2007
Highly Cited
2007
Increasing resistance to currently available influenza antivirals highlights the need to develop alternate approaches for the… Expand
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Highly Cited
2006
Highly Cited
2006
ABSTRACT Influenza is a highly infectious disease characterized by recurrent annual epidemics and unpredictable major worldwide… Expand
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