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D-aspartate oxidase activity

Known as: D-aspartate:oxygen oxidoreductase (deaminating), D-aspartic oxidase activity, aspartic oxidase activity 
Catalysis of the reaction: D-aspartate + H2O + O2 = oxaloacetate + NH3 + hydrogen peroxide. [EC:1.4.3.1]
National Institutes of Health

Papers overview

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2019
2019
Free d-aspartate triggers NMDA receptor-dependent cell death in primary cortical neurons and perturbs JNK activation, Tau phosphorylation, and protein SUMOylation in the cerebral cortex of mice…
In mammals, free d-aspartate (D-Asp) is abundant in the embryonic brain, while levels remain very low during adulthood as a… Expand
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2017
2017
Decreased free d-aspartate levels are linked to enhanced d-aspartate oxidase activity in the dorsolateral prefrontal cortex of schizophrenia patients
It is long acknowledged that the N-methyl d-aspartate receptor co-agonist, d-serine, plays a crucial role in several N-methyl d… Expand
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1975
1975
D-aspartate oxidase activity in extracts of mammalian central nervous tissue.
—d-Aspartate oxidase activity has been measured in water extracts of acetone powders prepared from cat forebrain, cerebellum and… Expand
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