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D-40TA

Known as: D40TA 
National Institutes of Health

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Estazolam

Papers overview

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1976
1976
Adrenocortical function, objective evaluation of the new tranquilizer D-40TA as agent for preanesthetic medication.
1974
1974
Metabolism of 8-chloro-6-phenyl-4H-s-triazolo(4,3-a)(1,4)-benzodiazepine (D-40TA), a new central depressant. I. Absorption, distribution and excretion in rats.
1. [14C]D–40TA was quantitatively absorbed from the rat small intestine by the portal route.2. The blood level of oral D–-40TA… 
1974
1974
The biotransformation of 8-chloro-6-phenyl-4H-s-triazolo(4,3-a) (1,4) benzodiazepine (D-40TA), a new central depressant, in man, dog and rat.
  • Y. Kanai
  • Xenobiotica; the fate of foreign compounds in…
  • 1974
  • Corpus ID: 26953533
1. Metabolic studies of 8-chloro-6-phenyl-4H-s-triazolo [4,3-a] [1,4] benzodiazepine (D—40TA) in man, dog and rat led to… 
1974
1974
Metabolism of 8-chloro-6-phenyl-4H-s-triazolo(4,3-a)(1,4)-benzodiazepine (D-40TA), a new central depressant. II. Species difference in metabolism.
1. Urinary and faecal excretion of radioactivity in 24 h after oral administration of [14C]D–40TA was 78% of the dose in dogs, 78… 
1974
1974
Metabolism of 8-chloro-6-phenyl-4H-s-triazolo(4,3-a)-(1,4)benzodiazepine (D-40TA), a new central depressant. IV. Placental transfer and excretion in milk in rats.
Abstract1. Placental transfer of [14C]D-40TA and [14C]nitrazepam was studied after intravenous injection to pregnant rats on the… 
1974
1974
Metabolism of 8-chloro-6-phenyl-4H-s-triazole(4,3-a)(1,4)benzodiazepine (D-40TA), a new central depressant. 3. Metabolism and tolerance studies in rats.
1. Induction in metabolism of D–40TA was studied in rats in relation to tolerance of its muscle relaxant effect. Pre-treatment… 
1974
1974
Neuropharmacological studies of effect of new central depressant, 8-chloro-6-phenyl-4H-s-triazolo (4,3-a) (1,4) benzodiazepine (D-40TA) on EEG and central sympathetic activating mechanism in cats.
The present study regarding the effects of 8-chloro-6-phenyl-4H-s-triazolo [4, 3-a] [1, 4] benzodiazepine (D-40TA) on the EEG… 
1974
1974
Comparative studies on the metabolic disposition of 8-chloro-6-phenyl-4H-s-triazolo(4,3-a)(1,4)benzodiazepine (D-40TA) and nitrazepam after single and repeated administration in rats.
Abstract1. Orally administered D-40TA was absorbed by rats with a maximum blood level at 30 min and a half-life of 60 min. The… 
1973
1973
Effects of new s-triazolobenzododiazepine (D-40TA) and other central muscle relaxants on spinal and supraspinal reflexes in cats.
The inhibitory effect of benzodiazepine-type agents such as 8-chloro-6-phenyl-4H-s-triazolo [4, 3a] [1, 4] benzodiazepine (D-40TA… 
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