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Cytokine Release Syndrome

A syndrome that occurs after therapeutic infusion of antibodies into the blood and is characterized by nausea, headache, tachycardia, hypotension… 
National Institutes of Health

Related topics

Related topics

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Immune System Diseases

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2020
Review
2020
Weathering the COVID-19 storm: Lessons from hematologic cytokine syndromes
Highly Cited
2020
Highly Cited
2020
Cytokine Release Syndrome (CRS) and Nicotine in COVID-19 Patients: Trying to Calm the Storm
SARS-CoV-2 is a new coronavirus that has caused a worldwide pandemic. It causes severe acute respiratory syndrome (COVID-19… 
Review
2020
Review
2020
Targeting JAK-STAT Signaling to Control Cytokine Release Syndrome in COVID-19
Review
2020
Review
2020
Targeting GM-CSF in COVID-19 Pneumonia: Rationale and Strategies
COVID-19 is a clinical syndrome ranging from mild symptoms to severe pneumonia that often leads to respiratory failure, need for… 
Highly Cited
2019
Highly Cited
2019
Preemptive Mitigation of CD19 CAR T Cell Cytokine Release Syndrome Without Attenuation of Anti-Leukemic Efficacy.
Immunotherapy with the adoptive transfer of T cells redirected with CD19-specific chimeric antigen receptors for B-lineage acute… 
Review
2019
Review
2019
Constitutive Inflammatory Cytokine Storm: A Major Threat to Human Health.
Immune cells secrete small protein molecules that aim for cell-cell communications. These small molecules are called cytokines… 
Review
2019
Review
2019
The UniCAR system: A modular CAR T cell approach to improve the safety of CAR T cells.
Highly Cited
2016
Highly Cited
2016
Maude SL, Teachey DT, Porter DL, Grupp SA. CD19-targeted chimeric antigen receptor T-cell therapy for acute lymphoblastic leukemia. Blood. 2015;125(26):4017-4023.
  • Blood
  • 2016
  • Corpus ID: 14417216
Teachey DT, Rheingold SR, Maude SL, et al. Cytokine release syndrome after blinatumomab treatment related to abnormal macrophage… 
Highly Cited
2013
Highly Cited
2013
Preclinical In Vivo Modeling of Cytokine Release Syndrome Induced by ErbB-Retargeted Human T Cells: Identifying a Window of Therapeutic Opportunity?
The ErbB network is dysregulated in many solid tumors. To exploit this, we have developed a chimeric Ag receptor (CAR) named… 
Highly Cited
2011
Highly Cited
2011
Preculture of PBMCs at high cell density increases sensitivity of T-cell responses, revealing cytokine release by CD28 superagonist TGN1412.
Human volunteers receiving TGN1412, a humanized CD28-specific monoclonal antibody, experienced a life-threatening cytokine… 
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