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Cytochrome P450 3A4 Inhibitor

Known as: CYP3A4 Inhibitor 
Any substance that inhibits the activity of the liver enzyme cytochrome P450 3A4. By inhibiting the activity of the CYP3A4 enzyme, the metabolism of… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Effect of Ticagrelor, a Cytochrome P450 3A4 Inhibitor, on the Pharmacokinetics of Tadalafil in Rats
Tadalafil is a cytochrome P450 (CYP) 3A4 substrate. Because there are few data on drug-drug interactions, it is advisable to take… 
Review
2016
Review
2016
Rhabdomyolysis caused by the moderate CYP3A4 inhibitor fluconazole in a patient on stable atorvastatin therapy: a case report and literature review
Rhabdomyolysis is a severe potential adverse drug reaction of statin therapy. We report a case of rhabdomyolysis due to drug–drug… 
2012
2012
Antimalarial interaction of quinine and quinidine with clarithromycin
SUMMARY Quinine (QN) and quinidine (QND) have been commonly used as effective and affordable antimalarials for over many years… 
2011
2011
Rapid Onset of Iatrogenic Adrenal Insufficiency in a Patient with Cystic Fibrosis–Related Liver Disease Treated with Inhaled Corticosteroids and a Moderate CYP3A4 Inhibitor
Objective: To report the rapid onset of adrenal insufficiency and subsequent development of Cushing syndrome precipitated by a… 
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