Cryofibrinogenemia

A 50-year-old woman presented with a history of painful lesions involving cold-exposed areas of skin, a condition that had… (More)

INTRODUCTION Cryofibrinogenemia may be essential, or secondary to diseases such as neoplasia, infection, thrombosis, and collagen… (More)

OBJECTIVE Cryofibrinogenemia is an under-recognized cryoprotein that can be life-threatening when untreated. Our aim was to… (More)

Factor V Leiden is the most common genetic thrombophilia in people of European descent, and is important to recognize as it can… (More)

Although the histologic characteristics of cryofibrinogenemia have been described in skin lesions, the literature is largely… (More)

An 86-year-old woman was admitted to hospital in March 2000 as a result of fatigue and typical Raynaud’s phenomenon of the hands… (More)

BACKGROUND Cutaneous manifestations of cryofibrinogenemia include purpura, ecchymosis, and ulcerations. The histology of these… (More)

Cryofibrinogenemia, a rare disease, is diagnosed by the presence of reversible cryoprecipitate in plasma, which may cause various… (More)

A 43-year-old monk had generalized purpura, arthritis of both shoulders, erythrocyanosis of lip and oral mucous membrane, Raynaud… (More)

A 23-year-old woman with factor XIII deficiency was presented. The patient had no consanguinity, but familial traits were present… (More)