Creatine Kinase B-Type, human

Known as: Creatine Kinase B-Type, CKB, Brain Creatine Kinase 
Creatine kinase B-type (381 aa, ~43 kDa) is encoded by the human CKB gene. This protein plays a role in both energy homeostasis and creatine… (More)
National Institutes of Health

Topic mentions per year

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1970-2016
0102019702016

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7 relations
CKB geneCreatine KinaseEnergy MetabolismEnzyme Gene
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Related mentions per year

Related mentions per year

1937-2018
19401960198020002020
Creatine Kinase B-Type, human
Energy Metabolism
Homeostasis
Creatine Kinase
Phosphotransferases
Phosphorylation

Papers overview

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2011
2011
Creatine kinase brain overexpression protects colorectal cells from various metabolic and non-metabolic stresses.
Creatine kinase brain (CKB) is one of three cytosolic isoforms of creatine kinase that is predominantly expressed in the brain… (More)
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Highly Cited
2006
Highly Cited
2006
Functional candidate genes in age-related macular degeneration: significant association with VEGF, VLDLR, and LRP6.
PURPOSE Age-related macular degeneration (AMD) is a retinal degenerative disease that is the leading cause of blindness worldwide… (More)
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2006
2006
Brain-type creatine kinase activates neuron-specific K+-Cl- co-transporter KCC2.
GABA, a major inhibitory neurotransmitter in the adult CNS, is excitatory at early developmental stages as a result of the… (More)
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2004
2004
Mice lacking the UbCKmit isoform of creatine kinase reveal slower spatial learning acquisition, diminished exploration and habituation, and reduced acoustic startle reflex responses
Brain-type creatine kinases B-CK (cytosolic) and UbCKmit (mitochondrial) are considered important for the maintenance and… (More)
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1991
1991
Structural characterization and tissue-specific expression of the mRNAs encoding isoenzymes from two rat mitochondrial creatine kinase genes.
Creatine kinase (CK; EC 2.7.3.2) isoenzymes play prominent roles in energy transduction. Mitochondrial CK (MtCK) reversibly… (More)
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1990
1990
Phosphorylation of chicken brain-type creatine kinase affects a physiologically important kinetic parameter and gives rise to protein microheterogeneity in vivo.
In addition to the two monomer subunits of chicken brain-type creatine kinase (B-CK, EC, 2.7.3.2), termed Bb (basic) and Ba… (More)
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1990
1990
Separate nuclear genes encode sarcomere-specific and ubiquitous human mitochondrial creatine kinase isoenzymes.
Creatine kinase (EC 2.7.3.2) isoenzymes play a central role in energy transduction. Nuclear genes encode creatine kinase subunits… (More)
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1989
1989
Isolation and characterization of the gene and cDNA encoding human mitochondrial creatine kinase.
Creatine kinase (CK; EC 2.7.3.2) isoenzymes play prominent roles in energy metabolism. Nuclear genes encode three known CK… (More)
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1980
1980
Mitochondrial CK (EC 2.7.3.2) in the human heart.
CKm, a mitochondrial form of CK, can be isolated from human cardiac muscle. It occurs in two forms, separable on the basis of the… (More)
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1979
1979
Creatine kinase isoenzymes of mitochondrial origin in human serum.
We measured creatine kinase (EC 2.7.3.2) activity in 1009 serum samples from 538 patients in the intensive-care units of the… (More)
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