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CpG Island Methylator Phenotype

Known as: CIMP, CIMP+ 
A phenotype whereby a subset of tumors are characterized by the simultaneous hypermethylation of multiple promoter-associated CpG islands.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
CpG Island Methylator Phenotype and Prognosis of Colorectal Cancer in Northeast China
Purpose. To investigate the association between CpG island methylator phenotype (CIMP) and the overall survival of sporadic… 
Review
2013
Review
2013
cCMP, cUMP, cTMP, cIMP and cXMP as possible second messengers: Development of a hypothesis based on studies with soluble guanylyl cyclase α1β1
Abstract Adenosine 3′,5′-cyclic monophosphate and guanosine 3′,5′-cyclic monophosphate are second messengers that regulate… 
2010
2010
CpG island hypermethylator phenotype in gastric carcinoma and its clinicopathological features
Gastric carcinoma (GC) is one of the human cancers in which promoter CpG island hypermethylation is frequently found. CpG island… 
2009
2009
MSH6 G39E polymorphism and CpG island methylator phenotype in colon cancer
The MSH6 G39E germline polymorphism is not associated with an increased risk of either microsatellite stable or unstable sporadic… 
2006
2006
[Correlations of CpG island methylator phenotype and OPCML gene methylation to carcinogenesis of hepatocellular carcinoma].
BACKGROUND & OBJECTIVE CpG island methylator phenotype (CIMP) is cancer-specific and involves in the promoter hypermethylation of… 
Highly Cited
2004
Highly Cited
2004
CMOS readout circuitry for ISFET microsystems
1999
1999
Sequence of Events Underlying the Allosteric Transition of Rod Cyclic Nucleotide–gated Channels
Activation of cyclic nucleotide–gated (CNG) ion channels involves a conformational change in the channel protein referred to as… 
Highly Cited
1989
Highly Cited
1989
Starfish oocyte maturation: evidence for a cyclic AMP-dependent inhibitory pathway.
Highly Cited
1983
Highly Cited
1983
Studies of two different intrachain cGMP-binding sites of cGMP-dependent protein kinase.
Highly Cited
1982
Highly Cited
1982
Proton nuclear magnetic resonance studies on cyclic nucleotide binding to the Escherichia coli adenosine cyclic 3',5'-phosphate receptor protein.
A 'H NMR study on the Escherichia coli aden- osine cyclic 3',5'-phosphate receptor protein (CRP) alone and in its complexes with… 
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