FAQ

Core Binding Factor Alpha 1 Subunit

Known as: SEF1 Protein, PEBP2-Alpha A, CBFA-1 Protein 
A transcription factor that dimerizes with CORE BINDING FACTOR BETA SUBUNIT to form core binding factor. It contains a highly conserved DNA-binding… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1983-2018
020406019832018

Related topics

Related topics

19 relations
Cleidocranial DysplasiaCore-Binding FactorDNA-Binding ProteinsGenes, Regulator
(More)

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Core Binding Factor Alpha 1 Subunit
Transcription, Genetic
physiological aspects
Transcriptional Regulation
dna binding
In Blood

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
Redifferentiation of dedifferentiated human articular chondrocytes: comparison of 2D and 3D cultures.
OBJECTIVE Three-dimensional (3D) cultures are widely used to redifferentiate chondrocytes. However, the rationale behind the… (More)
Is this relevant?
2012
2012
SOX9 gene transfer via safe, stable, replication-defective recombinant adeno-associated virus vectors as a novel, powerful tool to enhance the chondrogenic potential of human mesenchymal stem cells
Transplantation of genetically modified human bone marrow-derived mesenchymal stem cells (hMSCs) with an accurate potential for… (More)
  • figure 1
  • table 1
  • figure 2
  • table 2
  • figure 3
Is this relevant?
Highly Cited
2011
Highly Cited
2011
A Runx2/miR-3960/miR-2861 regulatory feedback loop during mouse osteoblast differentiation.
Our recent study showed that miR-2861 promotes osteoblast differentiation by targeting histone deacetylase 5, resulting in… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2010
2010
Multifunctional enhancers regulate mouse and human vitamin D receptor gene transcription.
The vitamin D receptor (VDR) mediates the endocrine actions of 1,25-dihydroxyvitamin D(3) [1,25(OH)(2)D(3)] and autoregulates the… (More)
Is this relevant?
2009
2009
Pro-osteogenic phenotype of human aortic valve interstitial cells is associated with higher levels of Toll-like receptors 2 and 4 and enhanced expression of bone morphogenetic protein 2.
OBJECTIVES Our aim was to determine whether aortic valve interstitial cells (AVICs) and pulmonary valve interstitial cells (PVICs… (More)
  • table 1
  • figure 1
  • table 2
  • figure 2
  • figure 2
Is this relevant?
2009
2009
JNK activity is essential for Atf4 expression and late-stage osteoblast differentiation.
Osteoblasts differentiate from mesodermal progenitors and play a pivotal role in bone formation and mineralization. Several… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2008
Highly Cited
2008
Compressive forces induce osteogenic gene expression in calvarial osteoblasts.
Bone cells and their precursors are sensitive to changes in their biomechanical environment. The importance of mechanical stimuli… (More)
Is this relevant?
2008
2008
Tumor cell cycle arrest induced by shear stress: Roles of integrins and Smad.
Interstitial flow in and around tumor tissue affects the mechanical microenvironment to modulate tumor cell growth and metastasis… (More)
  • table 1
  • figure 2
  • figure 1
  • figure 3
  • table 2
Is this relevant?
2004
2004
Runx2 deficiency in chondrocytes causes adipogenic changes in vitro.
Runx2 (runt-related transcription factor 2) is an important transcription factor for chondrocyte differentiation as well as for… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2002
Highly Cited
2002
Cbfβ interacts with Runx2 and has a critical role in bone development
Runx2 (runt-related transcription factor 2, also known as Cbfa1, Osf2 and AML3) is essential for bone development in mice, and… (More)
  • figure 1
  • figure 2
  • figure 4
  • figure 5
  • figure 6
Is this relevant?